Enzymatically oxidized lipids are a specific group of biomolecules that function as key
signaling mediators and hormones, regulating various cellular and physiological processes …

Oxylipins formed from polyunsaturated fatty acids (PUFAs) are the main mediators of PUFA
effects in the body. They are formed via cyclooxygenase, lipoxygenase, and cytochrome …

Eicosanoids have been implicated in a vast number of devastating inflammatory conditions,
including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different …

Background Cancer is a major burden of disease worldwide and increasing evidence shows
that inflammation contributes to cancer development and progression. Eicosanoids are …

The resolution of the inflammatory response is highly regulated by the timely biosynthesis of
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …

Lipoxins (LXs) or the lipoxygenase interaction products are generated from arachidonic acid
via sequential actions of lipoxygenases and subsequent reactions to give specific …

Maresins are a new family of anti-inflammatory and pro-resolving lipid mediators
biosynthesized from docosahexaenoic acid (DHA) by macrophages. Here we identified a …

The release and oxygenation of arachidonic acid is held to be a critical event in regulating
key processes in host defense, inflammation and hemodynamics [P--4]. oxygenation of …

Lipid-derived mediators play critical roles in inflammation and other multicellular vascular
processes, including atherosclerosis and thrombosis (1). The lipoxins (LXs) were first …

Lipoxins (LX) are trihydroxytetraene-containing eicosanoids that are generated within the
vascular lumen during platelet–leukocyte interactions and at mucosal surfaces via leukocyte …