BACKGROUND A time lapse system (TLS) is utilized in some fertility clinics with the aim of
predicting embryo viability and chance of live birth during IVF. It has been hypothesized that …

BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

Human beings are made of~ 50 trillion cells which arise from serial mitotic divisions of a
single cell-the fertilised egg. Remarkably, the early human embryo is often chromosomally …

STUDY QUESTION Can preimplantation genetic testing for aneuploidy (PGT-A) improve the
live birth rate and reduce the miscarriage rate in patients with recurrent pregnancy loss …

The health risks associated with transferring embryos classified as mosaic by
preimplantation genetic testing for aneuploidies (PGT-A) are currently unknown. Such …

The gain or loss of a chromosome—or aneuploidy—acts as one of the major triggers for
infertility and pregnancy loss in humans. These chromosomal abnormalities affect more than …

Aneuploidy that arises during meiosis and/or mitosis is a major contributor to early embryo
loss. We previously showed that human preimplantation embryos encapsulate …

The diagnosis of chromosomal mosaicism in the preimplantation and prenatal stage is
fraught with uncertainty and multiple factors need to be considered in order to gauge the …

STUDY QUESTION Is there an association between patients' reproductive history and the
mean euploidy rates per biopsied blastocysts (m-ER) or the live birth rates (LBRs) per first …

Objective To investigate whether the morphodynamic characterization of a euploid
blastocyst's development allows a higher prediction of a live birth after single-embryo …