Chemotherapy-induced peripheral neuropathy: where are we now?

LA Colvin - Pain, 2019 - journals.lww.com
Chemotherapy-induced peripheral neuropathy (CIPN) is a major challenge, with increasing
impact as oncological treatments, using potentially neurotoxic chemotherapy, improve …

Targeting strategies for oxaliplatin-induced peripheral neuropathy: clinical syndrome, molecular basis, and drug development

Y Yang, B Zhao, X Gao, J Sun, J Ye, J Li… - Journal of experimental & …, 2021 - Springer
Oxaliplatin (OHP)-induced peripheral neurotoxicity (OIPN) is a severe clinical problem and
potentially permanent side effect of cancer treatment. For the management of OIPN, accurate …

Patient-centric decision framework for treatment alterations in patients with Chemotherapy-induced Peripheral Neuropathy (CIPN)

DL Hertz, DS Childs, SB Park, S Faithfull, Y Ke… - Cancer treatment …, 2021 - Elsevier
Abstract Recently updated American Society of Clinical Oncology (ASCO) guidelines for
Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN) in …

Taxane and epothilone‐induced peripheral neurotoxicity: from pathogenesis to treatment

S Tamburin, SB Park, P Alberti… - Journal of the …, 2019 - Wiley Online Library
Taxane‐induced peripheral neurotoxicity (TIPN) is the most common non‐hematological
side effect of taxane‐based chemotherapy, and may result in dose reductions and …

Chemotherapy and peripheral neuropathy

T Li, D Mizrahi, D Goldstein, MC Kiernan, SB Park - Neurological Sciences, 2021 - Springer
Chemotherapy-induced peripheral neurotoxicity (CIPN) is a major dose-limiting side effect of
many anti-cancer agents, including taxanes, platinums, vinca alkaloids, proteasome …

Neurofilament light chain as a biomarker of axonal damage in sensory neurons and paclitaxel-induced peripheral neuropathy in patients with ovarian cancer

C Mortensen, KD Steffensen, E Simonsen, K Herskind… - Pain, 2023 - journals.lww.com
Paclitaxel-induced peripheral neuropathy (PIPN) is a barrier to effective cancer treatment
and impacts quality of life among patients with cancer. We used a translational approach to …

[PDF][PDF] Prevention and therapy of chemotherapy-induced peripheral neuropathy: a review of recent findings

Z Michalova, E Székiová, J Blaško, I Vanický - Neoplasma, 2023 - researchgate.net
Chemotherapy-induced peripheral neuropathy is one of the most frequent dose-limiting side
effects, observed in patients receiving antineoplastic agents, persisting for up to two years …

P‐Glycoprotein inhibition exacerbates paclitaxel neurotoxicity in neurons and patients with cancer

TB Stage, C Mortensen, S Khalaf… - Clinical …, 2020 - Wiley Online Library
Paclitaxel‐induced peripheral neuropathy (PIPN) is a common and dose‐limiting adverse
event. The role of P‐glycoprotein (P‐gp) in the neuronal efflux of paclitaxel was assessed …

[HTML][HTML] Risk factors of paclitaxel-induced peripheral neuropathy in patients with breast cancer: a prospective cohort study

S Lixian, Y Xiaoqian, G Luyan, Z Lizhi, D Rui… - Frontiers in …, 2024 - frontiersin.org
Objective Chemotherapy-induced peripheral neuropathy (CIPN) is a common and severe
adverse reaction in taxane-based chemotherapy. This study aimed to analyze the risk …

[HTML][HTML] An Emerging Aspect of Cancer Neuroscience: A Literature Review on Chemotherapy-induced Peripheral Neuropathy

Z Tao, Z Chen, X Zeng, J Cui, M Quan - Cancer Letters, 2024 - Elsevier
The nervous system governs both ontogeny and oncology. Foundational discoveries have
clarified the direct communication of neurotransmitters with tumors and indirect interactions …