Nanotherapeutics for Alleviating Anesthesia‐Associated Complications

B Lu, L Wei, G Shi, J Du - Advanced Science, 2024 - Wiley Online Library
Current management of anesthesia‐associated complications falls short in terms of both
efficacy and safety. Nanomaterials with versatile properties and unique nano‐bio …

Nanoencapsulation of general anaesthetics

BMT Abdoullateef, SED Al-Mofty, HME Azzazy - Nanoscale Advances, 2024 - pubs.rsc.org
General anaesthetics are routinely used to sedate patients during prolonged surgeries and
administered via intravenous injection and/or inhalation. All anaesthetics have short half …

Investigation of cyclodextrin-based nanosponges for solubility and bioavailability enhancement of rilpivirine

MRP Rao, J Chaudhari, F Trotta, F Caldera - Aaps Pharmscitech, 2018 - Springer
Rilpivrine is BCS class II drug used for treatment of HIV infection. The drug has low aqueous
solubility (0.0166 mg/ml) and dissolution rate leading to low bioavailability (32%). Aim of this …

Enhancement of bioavailability of non-nucleoside reverse transciptase inhibitor using nanosponges

MRP Rao, C Shirsath - AAPS PharmSciTech, 2017 - Springer
Efavirenz is a non-nucleoside reverse transcriptase inhibitor which is chronically prescribed
for HIV patients. However, it exhibits solubility-limited bioavailability. Aim of this work was to …

Nanostructured lipid carrier of propofol: a promising alternative to marketed soybean oil–based nanoemulsion

G Shevalkar, R Pai, P Vavia - AAPS PharmSciTech, 2019 - Springer
Nanostructured lipid carrier (NLC) of propofol was formulated using hot emulsification-probe
sonication method for improvising its parenteral delivery by reducing pain on injection and …

A Review on Nanosponges: An Idiosyncratic Approach for Delivery of Proactive Molecules

M Attri, A Raghav, K Rao, P Pandey… - Current …, 2024 - ingentaconnect.com
Background: A lot of work has been done by many researchers to develop a system that is
targeted at a specific site. Nanosponges are one of the systems that serve this purpose and …

Physicochemical characterization and pharmacological evaluation of novel propofol micelles with low-lipid and low-free propofol

Y Chu, T Sun, Z Xie, K Sun, C Jiang - Pharmaceutics, 2022 - mdpi.com
We developed safe and stable mixed polymeric micelles with low lipids and free propofol for
intravenous administration, to overcome the biological barrier of the reticuloendothelial …

Simultaneous quantification of DPPG, DEPC and cholesterol in propofol liposome by HPLC-ELSD using alkaline hydrolysis

J Shen, Z Chen, F Yue, Y Li, Z Xu… - Journal of …, 2020 - academic.oup.com
A high-performance liquid chromatography method with evaporative light-scattering
detection (ELSD) was performed for simultaneous determination of dipalmitoyl …

The role of antibiotics, catecholamines and sedatives on immune cell functionality and mitochondrial activity.

M Miller - 2022 - discovery.ucl.ac.uk
Introduction and aim: Sepsis is defined as life-threatening organ dysfunction caused by a
dysregulated host response to infection. In the absence of host-modulating therapies …

[PDF][PDF] High-Performance Liquid Chromatography Assessment of Propofol Stability in Pharmaceuticals

HU Chikhale - Asian Journal of Pharmaceutics (AJP), 2024 - asiapharmaceutics.info
High-Performance Liquid Chromatography Assessment of Propofol Stability in Pharmaceuticals
Page 1 Asian Journal of Pharmaceutics • Apr-Jun 2024 • 18 (2) | 446 High-Performance Liquid …