The gastrointestinal tract is the only internal organ to have evolved with its own independent
nervous system, known as the enteric nervous system (ENS). This Review provides an …

The gut microbiota has emerged as an environmental factor that modulates the development
of the central nervous system (CNS) and the enteric nervous system (ENS). Before obtaining …

The cellular landscape of the human intestinal tract is dynamic throughout life, developing in
utero and changing in response to functional requirements and environmental exposures …

The enteric nervous system (ENS) of the gastrointestinal tract controls many diverse
functions, including motility and epithelial permeability. Perturbations in ENS development …

Autonomous regulation of the intestine requires the combined activity of functionally distinct
neurons of the enteric nervous system (ENS). However, the variety of enteric neuron types …

Hirschsprung disease is defined by the absence of enteric neurons at the end of the bowel.
The enteric nervous system (ENS) is the intrinsic nervous system of the bowel and regulates …

The gastrointestinal tract contains its own set of intrinsic neuroglial circuits—the enteric
nervous system (ENS)—which detects and responds to diverse signals from the …

Elucidation of the cellular identity of neuronal precursors provides mechanistic insights into
the development and pathophysiology of the nervous system. In the enteric nervous system …

SOX10 belongs to a family of 20 SRY (sex-determining region Y)-related high mobility group
box-containing (SOX) proteins, most of which contribute to cell type specification and …

In this Review we summarize our current understanding of the biology of mesenchymal cells
of the intestinal lamina propria focusing mainly on fibroblasts and myofibroblasts. The topics …