Polymyositis and dermatomyositis are inflammatory myopathies that differ in their clinical
features, histopathology, response to treatment, and prognosis. Although their clinical …

Where are we moving in the classification of idiopathic infl... : Current Opinion in Neurology
Where are we moving in the classification of idiopathic inflammatory myopathies? : Current …

Dermatomyositis is an acquired auto-immune disease characterized by skin lesions and
muscle-specific pathological features such as perifascicular muscle fibre atrophy and …

Objective Activation of the type 1 interferon (IFN1) pathway is a prominent feature of
dermatomyositis (DM) muscle and may play a role in the pathogenesis of this disease …

Inclusion body myositis is a late onset treatment-refractory autoimmune disease of skeletal
muscle associated with a blood autoantibody (anti-cN1A), an HLA autoimmune haplotype …

The classification of idiopathic inflammatory myopathies (IIM) is based on clinical,
serological and histological criteria. The identification of myositis‐specific antibodies has …

Autoimmune diseases develop as a result of chronic inflammation owing to interactions
between genes and the environment. However, the mechanisms by which autoimmune …

Objective: To evaluate the diagnostic value of myxovirus resistance A (MxA) expression in
the cytoplasm of myofibers in the diagnosis of dermatomyositis (DM). Methods: We assessed …

Activation of p53 tumor suppressor by antagonizing its negative regulator murine double
minute (MDM) 2 has been considered an attractive strategy for cancer therapy and several …

Objective Immune‐mediated necrotizing myopathies (IMNM) may be associated with either
anti–signal recognition protein (SRP) or anti–3‐hydroxy‐3‐methylglutaryl‐CoA reductase …