“K2” and “Spice” drugs (collectively hereafter referred to as Spice) represent a relatively new
class of designer drugs that have recently emerged as popular alternatives to marijuana …

Synthetic cannabinoids are functionally similar to delta9-tetrahydrocannabinol (THC), the
psychoactive principle of cannabis, and bind to the same cannabinoid receptors in the brain …

Aims Recently, several synthetic cannabinoids were identified in herbal mixtures consumed
as recreational drugs alternative to cannabis products. The aim was to characterize the …

Consumption of synthetic mind-altering compounds, also known as “new psychoactive
substances,” is increasing globally at an alarming rate. Synthetic cannabinoids (SCs) are …

STUDY OBJECTIVE: Δ-9-Tetrahydrocannabinol homologs have been increasingly abused
since their introduction in 2004. Such products were used as a “legal high” for those wishing …

Introduction: The emergence of novel psychoactive substances has changed the
epidemiology of drugs used recreationally throughout Europe and have posed significant …

New psychoactive substances (NPSs), sometimes referred to as “legal highs” in more
colloquial environments/the media, are a class of compounds that have been recently made …

We identified two new-type cannabimimetic quinolinyl carboxylates, quinolin-8-yl 1-pentyl-(1
H-indole)-3-carboxylate (QUPIC, 1) and quinolin-8-yl 1-(cyclohexylmethyl)-1 H-indole-3 …

A new class of synthetic cannabinoids has emerged as new psychoactive substances
(NPS). Similar in structure to JWH‐022, these substances contain alkene modifications to …

The analysis of synthetic cannabinoids in human matrices is of particular importance in the
fields of forensic and clinical toxicology since cannabis users partly shift to the consumption …