Hazardous compounds in tobacco smoke

R Talhout, T Schulz, E Florek, J Van Benthem… - International journal of …, 2011 - mdpi.com
Tobacco smoke is a toxic and carcinogenic mixture of more than 5,000 chemicals. The
present article provides a list of 98 hazardous smoke components, based on an extensive …

Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

S Adler, D Basketter, S Creton, O Pelkonen… - Archives of …, 2011 - Springer
The 7th amendment to the EU Cosmetics Directive prohibits to put animal-tested cosmetics
on the market in Europe after 2013. In that context, the European Commission invited …

Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals

EFSA Scientific Committee, SJ More, V Bampidis… - Efsa …, 2019 - Wiley Online Library
This Guidance document describes harmonised risk assessment methodologies for
combined exposure to multiple chemicals for all relevant areas within EFSA's remit, ie …

Criteria for the Research Institute for fragrance materials, Inc.(RIFM) safety evaluation process for fragrance ingredients

AM Api, D Belsito, M Bruze, P Cadby, P Calow… - Food and Chemical …, 2015 - Elsevier
Abstract The Research Institute for Fragrance Materials, Inc.(RIFM) has been engaged in the
generation and evaluation of safety data for fragrance materials since its inception over 45 …

Guidance on the use of the Threshold of Toxicological Concern approach in food safety assessment

EFSA Scientific Committee, SJ More, V Bampidis… - EFSA …, 2019 - Wiley Online Library
Abstract The Scientific Committee confirms that the Threshold of Toxicological Concern
(TTC) is a pragmatic screening and prioritisation tool for use in food safety assessment. This …

Guidance on the use of the Threshold of Toxicological Concern approach in food safety assessment

EFSA Scientific Committee - 2019 - opinvisindi.is
The Scientific Committee confirms that the Threshold of Toxicological Concern (TTC) is a
pragmatic screening and prioritisation tool for use in food safety assessment. This Guidance …

[HTML][HTML] Special aspects of cosmetic spray safety evaluations: principles on inhalation risk assessment

H Rothe, R Fautz, E Gerber, L Neumann, K Rettinger… - Toxicology letters, 2011 - Elsevier
The consumer exposure to the vast majority of cosmetic products is limited to dermal contact.
Even spray applications tend to be topically exposed to skin or hair. Besides this skin …

Advances in acute toxicity testing: strengths, weaknesses and regulatory acceptance

EO Erhirhie, CP Ihekwereme, EE Ilodigwe - Interdisciplinary toxicology, 2018 - sciendo.com
Safety assessment of chemicals, pharmaceuticals, food and food ingredients, cosmetics,
industrial products is very crucial prior to their approval for human uses. Since the …

Flavour chemicals, synthetic coolants and pulegone in popular mint-flavoured and menthol-flavoured e-cigarettes

EE Omaiye, W Luo, KJ McWhirter… - Tobacco …, 2022 - tobaccocontrol.bmj.com
Background The Food and Drug Administration (FDA) has recently banned flavours from
pod-style electronic cigarettes (e-cigarettes), except for menthol and tobacco. JUUL …

Scientific Opinion on Exploring options for providing advice about possible human health risks based on the concept of Threshold of Toxicological Concern (TTC)

EFSA Scientific Committee - EFSA journal, 2012 - Wiley Online Library
Synthetic and naturally occurring substances present in food and feed, together with their
possible breakdown or reaction products, represent a large number of substances, many of …