Inflammation and skeletal muscle wasting during cachexia

JM Webster, LJAP Kempen, RS Hardy… - Frontiers in …, 2020 - frontiersin.org
Cachexia is the involuntary loss of muscle and adipose tissue that strongly affects mortality
and treatment efficacy in patients with cancer or chronic inflammatory disease. Currently, no …

[HTML][HTML] Advances in muscle health and nutrition: a toolkit for healthcare professionals

CM Prado, F Landi, STH Chew, PJ Atherton, J Molinger… - Clinical Nutrition, 2022 - Elsevier
Low muscle mass and malnutrition are prevalent conditions among adults of all ages, with
any body weight or body mass index, and with acute or chronic conditions, including COVID …

Mechanisms regulating muscle regeneration: insights into the interrelated and time-dependent phases of tissue healing

L Forcina, M Cosentino, A Musarò - Cells, 2020 - mdpi.com
Despite a massive body of knowledge which has been produced related to the mechanisms
guiding muscle regeneration, great interest still moves the scientific community toward the …

An overview about the biology of skeletal muscle satellite cells

L Forcina, C Miano, L Pelosi, A Musarò - Current genomics, 2019 - ingentaconnect.com
The peculiar ability of skeletal muscle tissue to operate adaptive changes during post-natal
development and adulthood has been associated with the existence of adult somatic stem …

Neuromuscular junction as an entity of nerve-muscle communication

E Lepore, I Casola, G Dobrowolny, A Musarò - Cells, 2019 - mdpi.com
One of the crucial systems severely affected in several neuromuscular diseases is the loss of
effective connection between muscle and nerve, leading to a pathological non …

Signals from the niche: insights into the role of IGF-1 and IL-6 in modulating skeletal muscle fibrosis

L Forcina, C Miano, BM Scicchitano, A Musarò - Cells, 2019 - mdpi.com
Muscle regeneration, characterized by the activation and proliferation of satellite cells and
other precursors, is accompanied by an inflammatory response and the remodeling of the …

Docosahexaenoic acid, a potential treatment for sarcopenia, modulates the ubiquitin–proteasome and the autophagy–lysosome systems

JH Lee, JH Jeon, MJ Lee - Nutrients, 2020 - mdpi.com
One of the characteristic features of aging is the progressive loss of muscle mass, a
nosological syndrome called sarcopenia. It is also a pathologic risk factor for many clinically …

Increased circulating levels of interleukin‐6 affect the redox balance in skeletal muscle

L Forcina, C Miano, BM Scicchitano… - Oxidative Medicine …, 2019 - Wiley Online Library
The extent of oxidative stress and chronic inflammation are closely related events which
coexist in a muscle environment under pathologic conditions. It has been generally …

Can conditions of skeletal muscle loss be improved by combining exercise with anabolic–androgenic steroids? A systematic review and meta-analysis of testosterone …

H Falqueto, JLR Júnior, MNO Silvério… - Reviews in Endocrine …, 2021 - Springer
Sarcopenia, cachexia, and atrophy due to inactivity and disease states are characterized by
a loss of skeletal muscle mass, often accompanied by reduced levels of anabolic hormones …

[HTML][HTML] Quorum sensing molecules as a novel microbial factor impacting muscle cells

A De Spiegeleer, D Elewaut… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Skeletal muscle makes up the largest part of human body mass and a good maintenance of
this organ is essential for general health. In accordance, muscle wasting, a frequent …