Mass spectrometry-based zebrafish toxicometabolomics: a review of analytical and data quality challenges

KM da Silva, E Iturrospe, C Bars, D Knapen… - Metabolites, 2021 - mdpi.com
Metabolomics has achieved great progress over the last 20 years, and it is currently
considered a mature research field. As a result, the number of applications in toxicology …

Adolescent kratom exposure affects cognitive behaviours and brain metabolite profiles in Sprague-Dawley rats

AN Zul Aznal, NA Mohamad Nor Hazalin… - Frontiers in …, 2022 - frontiersin.org
Adolescence is a critical developmental period during which exposure to psychoactive
substances like kratom (Mitragyna speciosa) can cause long-lasting deleterious effects …

Systematic review and meta-analysis of 10 years of unpredictable chronic stress in zebrafish

M Gallas-Lopes, LM Bastos, R Benvenutti… - Lab Animal, 2023 - nature.com
The zebrafish (Danio rerio) is a model animal that is being increasingly used in
neuroscience research. A decade ago, the first study on unpredictable chronic stress (UCS) …

[HTML][HTML] The anxiolytic-like activity of water-soluble Moringa oleifera Lam. lectin is mediated via serotoninergic, noradrenergic, and dopaminergic neurotransmission

LL de Siqueira Patriota, BRF de Lima… - Brain Disorders, 2023 - Elsevier
Lectins are carbohydrate-binding proteins that exhibit several biological activities, including
modulatory effects on the central nervous system. In this study, we evaluated whether the …

Applying newly suggested simultaneous analysis of metabolomics and lipidomics into perfluorooctanesulfonate-derived neurotoxicity mechanism in zebrafish …

EK Min, SY Park, KH Liu, KT Kim - Journal of Hazardous Materials, 2025 - Elsevier
Developing methodologies for performing multi-omics with one sample has been
challenging in zebrafish toxicology; however, related studies are lacking. A new strategy for …

[PDF][PDF] Modulation impacts of Moringa oleifera on thermo tolerance parameters and blood indices in subtropical ewes under heat stress

A Al Mufarji, AA Mohammed, R Al Zeidi… - Adv. Anim. Vet …, 2022 - researchgate.net
Appropriate strategies are required for the alleviation of heat stress resulting from global
warming contributing to impaired metabolism and dysregulated immune and reproductive …

Neuropharmacological potential of Mimosa tenuiflora in adult zebrafish: An integrated approach to GABAergic and serotonergic neuromodulation

JIF de Araújo, GA do Nascimento… - Behavioural Brain …, 2025 - Elsevier
Abstract Mimosa tenuiflora (" jurema-preta") is traditionally used in folk medicine for various
diseases. The study investigated the neuropharmacological potential of Mimosa tenuiflora …

Efficacy of Hot Tea Infusion vs. Ethanolic Extract of Moringa oleifera for the Simultaneous Treatment of Nonalcoholic Fatty Liver, Hyperlipidemia, and Hyperglycemia …

SI Cortes-Alvarez, I Delgado-Enciso… - Journal of Nutrition …, 2024 - Wiley Online Library
Moringa oleifera (MO) is a native tree of Asia and is cultivated in some areas of Mexico as
part of traditional horticulture. The aim of the present study was to compare the efficacy of …

Persicaria minor ameliorates the cognitive function of chronic cerebral hypoperfusion rats: Metabolomic analysis and potential mechanisms

LW Chun, RK Ramachandran, SFF Othman… - Behavioural Brain …, 2023 - Elsevier
Persicaria minor (P. minor) is a herbal plant with many uses in food, perfume, and the
medical industry. P. minor extract contains flavonoids with antioxidant and …

Kratom (M. speciosa) exposure during adolescence caused long-lasting cognitive behavioural deficits associated with perturbated brain metabolism pathways in adult …

FW Suhaimi, ANZ Aznal, NAMN Hazalin, LK Teh… - Behavioural Brain …, 2023 - Elsevier
Kratom (M. speciosa Korth) is an herbal plant native to Southeast Asia. The leaves have
been widely used to alleviate pain and opioid withdrawal symptoms. However, the …