The world population is ageing rapidly. As society ages, the incidence of physical limitations
is dramatically increasing, which reduces the quality of life and increases healthcare …

As the global population ages, older decision makers will be required to take greater
responsibility for their own physical, psychological and financial well-being. With this in …

In 2008, we published an article arguing that the age-related loss of muscle strength is only
partially explained by the reduction in muscle mass and that other physiologic factors …

Anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward
motivation, and/or deficits in reward-related learning, is a common feature of depression …

Stress can be defined as a brain–body reaction towards stimuli arising from the environment
or from internal cues that are interpreted as a disruption of homeostasis. The organization of …

The variability in the response to antipsychotic medication in schizophrenia may reflect
between-patient differences in neurobiology. Recent cross-sectional neuroimaging studies …

Recent evidence clearly indicates that muscle weakness associated with aging is not
entirely explained by classically postulated atrophy of muscle. In this issue, which focuses …

Aging is a physiological process that can develop without the appearance of concurrent
diseases. However, very frequently, older people suffer from memory loss and an …

Metabolic networks and their dysfunction in the brain are closely associated with central
nervous function and many psychogenic diseases. Thus, it is of utmost importance to …

Deep brain stimulation (DBS) has been used as a treatment of movement disorders such as
Parkinson's disease, dystonia, and essential tremor for over twenty years, and is a promising …