Hypertensive eye disease

CY Cheung, V Biousse, PA Keane… - Nature Reviews …, 2022 - nature.com
Hypertensive eye disease includes a spectrum of pathological changes, the most well
known being hypertensive retinopathy. Other commonly involved parts of the eye in …

Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis

C Czakó, T Kovács, Z Ungvari, A Csiszar… - Geroscience, 2020 - Springer
Cognitive impairment and dementia are major medical, social, and economic public health
issues worldwide with significant implications for life quality in older adults. The leading …

Deep learning of the retina enables phenome-and genome-wide analyses of the microvasculature

SM Zekavat, VK Raghu, M Trinder, Y Ye, S Koyama… - Circulation, 2022 - Am Heart Assoc
Background: The microvasculature, the smallest blood vessels in the body, has key roles in
maintenance of organ health and tumorigenesis. The retinal fundus is a window for human …

Microvascular network alterations in the retina of patients with Alzheimer's disease

CY Cheung, YT Ong, MK Ikram, SY Ong, X Li… - Alzheimer's & …, 2014 - Elsevier
Background Although cerebral small-vessel disease has been implicated in the
development of Alzheimer's disease (AD), the cerebral microcirculation is difficult to …

Retinal microvasculature as a model to study the manifestations of hypertension

CY Cheung, MK Ikram, C Sabanayagam, TY Wong - Hypertension, 2012 - Am Heart Assoc
The retinal vasculature allows direct noninvasive visualization of the body's
mircrovasculature. Because the retina and other end organs (brain and kidney) share similar …

Quantitative and qualitative retinal microvascular characteristics and blood pressure

CY Cheung, WT Tay, P Mitchell, JJ Wang… - Journal of …, 2011 - journals.lww.com
Objective The present study examined the effects of blood pressure on a spectrum of
quantitative and qualitative retinal microvascular signs. Methods Retinal photographs from …

Retinal vasculature in glaucoma: a review

KKW Chan, F Tang, CCY Tham, AL Young… - BMJ open …, 2017 - bmjophth.bmj.com
Despite the critical impact of glaucoma on global blindness, its aetiology is not fully
characterised. Elevated intraocular pressure is highly associated with glaucomatous optic …

[HTML][HTML] Retinal microvascular network attenuation in Alzheimer's disease

MA Williams, AJ McGowan, CR Cardwell… - Alzheimer's & Dementia …, 2015 - Elsevier
Introduction Cerebral small-vessel disease has been implicated in the development of
Alzheimer's disease (AD). The retinal microvasculature enables the noninvasive …

[HTML][HTML] The eye, the kidney, and cardiovascular disease: old concepts, better tools, and new horizons

TE Farrah, B Dhillon, PA Keane, DJ Webb, N Dhaun - Kidney international, 2020 - Elsevier
Chronic kidney disease (CKD) is common, with hypertension and diabetes mellitus acting as
major risk factors for its development. Cardiovascular disease is the leading cause of death …

Peripapillary microvascular and neural changes in diabetes mellitus: an OCT-angiography study

S Vujosevic, A Muraca, V Gatti… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: To evaluate peripapillary vessel density and morphology in patients with diabetes
mellitus (DM) without clinical signs of diabetic retinopathy (DR) and with mild …