Ferritins are spherical iron storage proteins within cells, composed of 24 subunits of two
types, heavy-chain ferritin (HFn) and light-chain ferritin. Ferritins auto-assemble naturally …

In spite of the successful use of monoclonal antibodies (mAbs) in clinic for tumor treatment,
their applications are still hampered in therapeutic development due to limitations, such as …

Compared with other nanocarriers such as liposomes, mesoporous silica, and cyclodextrin,
ferritin as a typical protein nanocage has received considerable attention in the field of food …

Objective: A protein-based leaking-proof theranostic nanoplatform for dual-modality imaging-
guided tumor photodynamic therapy (PDT) has been designed. Impact Statement: A site …

Combination of natural agents has received a great attention in cancer treatment because of
synergistically increased apoptotic effect on cancer cell lines by triggering several apoptotic …

Ferritin may serve as a nanocarrier for the selective delivery of anticancer metallodrugs.
Here, we have prepared and characterized a well-defined conjugate between the gold drug …

Herein, we report on the successful encapsulation into human H-ferritin of two highly
charged Ru (II) polypyridyl complexes,[Ru (phen) 2L′] 2+(Ru1, with L′= 4, 4′-(2, 5, 8, 11 …

Protein metalation is a process that determines the formation of adducts upon reaction of
metal compounds with proteins. Protein metalation plays a crucial role in different fields …

Cancer is a disease that seriously threatens human health. Based on the improvement of
traditional treatment methods and the development of new treatment modes, the pattern of …

Aurothiomalate (AuTM) is an FDA‐approved antiarthritic gold drug with unique anticancer
properties. To enhance its anticancer activity, we prepared a bioconjugate with human …