Increasing the production of the bioactive compounds in medicinal mushrooms: an omics perspective

N Arshadi, H Nouri, H Moghimi - Microbial Cell Factories, 2023 - Springer
Macroscopic fungi, mainly higher basidiomycetes and some ascomycetes, are considered
medicinal mushrooms and have long been used in different areas due to their …

From nutraceutical to clinical trial: frontiers in Ganoderma development

KD Hsu, KC Cheng - Applied microbiology and biotechnology, 2018 - Springer
Ganoderma spp. are medical mushrooms with various pharmacological compounds which
are regarded as a nutraceutical for improving health and treating diseases. This review …

Secondary metabolites from Ganoderma

S Baby, AJ Johnson, B Govindan - Phytochemistry, 2015 - Elsevier
Ganoderma is a genus of medicinal mushrooms. This review deals with secondary
metabolites isolated from Ganoderma and their biological significance. Phytochemical …

Ganoderma lucidum: A potential pleiotropic approach of ganoderic acids in health reinforcement and factors influencing their production

MF Ahmad, S Wahab, FA Ahmad, SA Ashraf… - Fungal Biology …, 2022 - Elsevier
Ganoderma lucidum (G. lucidum) main attractive pharmacological characteristics are
antitumor and immunomodulatory activities which are chiefly associated with its two …

Fungal strain matters: colony growth and bioactivity of the European medicinal polypores Fomes fomentarius, Fomitopsis pinicola and Piptoporus betulinus

P Dresch, MN D´ Aguanno, K Rosam, U Grienke… - Amb Express, 2015 - Springer
Polypores have been applied in traditional Chinese medicine up to the present day, and are
becoming more and more popular worldwide. They show a wide range of bioactivities …

Functional analysis of the role of glutathione peroxidase (GPx) in the ROS signaling pathway, hyphal branching and the regulation of ganoderic acid biosynthesis in …

C Li, L Shi, D Chen, A Ren, T Gao, M Zhao - Fungal Genetics and Biology, 2015 - Elsevier
Ganoderma lucidum, a hallmark of traditional Chinese medicine, has been widely used as a
pharmacologically active compound. Although numerous research studies have focused on …

Molecular regulation of fungal secondary metabolism

W Yu, R Pei, J Zhou, B Zeng, Y Tu, B He - World Journal of Microbiology …, 2023 - Springer
Many bioactive secondary metabolites synthesized by fungi have important applications in
many fields, such as agriculture, food, medical and others. The biosynthesis of secondary …

Hydrogen‐rich water regulates effects of ROS balance on morphology, growth and secondary metabolism via glutathione peroxidase in Ganoderma lucidum

A Ren, R Liu, ZG Miao, X Zhang, PF Cao… - Environmental …, 2017 - Wiley Online Library
Ganoderma lucidum is one of the most important medicinal fungi, but the lack of basic study
on the fungus has hindered the further development of its value. To investigate the roles of …

[HTML][HTML] SA inhibits complex III activity to generate reactive oxygen species and thereby induces GA overproduction in Ganoderma lucidum

R Liu, P Cao, A Ren, S Wang, T Yang, T Zhu, L Shi… - Redox Biology, 2018 - Elsevier
Ganoderma lucidum has high commercial value because it produces many active
compounds, such as ganoderic acids (GAs). Salicylic acid (SA) was previously reported to …

[HTML][HTML] Heat stress-induced reactive oxygen species participate in the regulation of HSP expression, hyphal branching and ganoderic acid biosynthesis in …

R Liu, X Zhang, A Ren, DK Shi, L Shi, J Zhu… - Microbiological …, 2018 - Elsevier
Heat stress (HS) is an important environmental factor that affects the growth and metabolism
of edible fungi, but the molecular mechanism of the heat stress response (HSR) remains …