The gut microbiome and mental health: advances in research and emerging priorities

AP Shoubridge, JM Choo, AM Martin, DJ Keating… - Molecular …, 2022 - nature.com
The gut microbiome exerts a considerable influence on human neurophysiology and mental
health. Interactions between intestinal microbiology and host regulatory systems have now …

Remodeling of microbiota gut-brain axis using psychobiotics in depression

MSK Palepu, MP Dandekar - European journal of pharmacology, 2022 - Elsevier
Depression is a multifaceted psychiatric disorder mainly orchestrated by dysfunction of
neuroendocrine, neurochemical, immune, and metabolic systems. The interconnection of …

[HTML][HTML] Psycho-pharmacomicrobiomics: a systematic review and meta-analysis

A Minichino, T Preston, JB Fanshawe, P Fusar-Poli… - Biological …, 2024 - Elsevier
Background Understanding the interactions between the gut microbiome and psychotropic
medications (psycho-pharmacomicrobiomics) could improve treatment stratification …

Modulatory effect of gut microbiota on the gut-brain, gut-bone axes, and the impact of cannabinoids

I Ibrahim, S Syamala, JA Ayariga, J Xu, BK Robertson… - Metabolites, 2022 - mdpi.com
The gut microbiome is a collection of microorganisms and parasites in the gastrointestinal
tract. Many factors can affect this community's composition, such as age, sex, diet …

Targeting the endocannabinoid system for the treatment of abdominal pain in irritable bowel syndrome

SM Brierley, B Greenwood-Van Meerveld… - Nature Reviews …, 2023 - nature.com
The management of visceral pain in patients with disorders of gut–brain interaction, notably
irritable bowel syndrome, presents a considerable clinical challenge, with few available …

Anti-microbial activity of phytocannabinoids and endocannabinoids in the light of their physiological and pathophysiological roles

RV Sionov, D Steinberg - Biomedicines, 2022 - mdpi.com
Antibiotic resistance has become an increasing challenge in the treatment of various
infectious diseases, especially those associated with biofilm formation on biotic and abiotic …

Effects of repeated lysergic acid diethylamide (LSD) on the mouse brain endocannabinoidome and gut microbiome

A Inserra, G Giorgini, S Lacroix… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Psychedelics elicit prosocial, antidepressant and anxiolytic effects
via neuroplasticity, neurotransmission and neuro‐immunomodulatory mechanisms. Whether …

Palmitoylethanolamide counteracts high-fat diet-induced gut dysfunction by reprogramming microbiota composition and affecting tryptophan metabolism

C Pirozzi, L Coretti, N Opallo, M Bove… - Frontiers in …, 2023 - frontiersin.org
Obesity is associated with gastrointestinal (GI) tract and central nervous system (CNS)
disorders. High-fat diet (HFD) feeding-induced obesity in mice induces dysbiosis, causing a …

[HTML][HTML] Endocannabinoid anandamide attenuates acute respiratory distress syndrome through modulation of microbiome in the gut-lung axis

M Sultan, K Wilson, OA Abdulla, PB Busbee, A Hall… - Cells, 2021 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a serious lung condition characterized by
severe hypoxemia leading to limitations of oxygen needed for lung function. In this study, we …

Effects of non-polar dietary and endogenous lipids on gut microbiota alterations: the role of lipidomics

K Tsiantas, SJ Konteles, E Kritsi, VJ Sinanoglou… - International Journal of …, 2022 - mdpi.com
Advances in sequencing technologies over the past 15 years have led to a substantially
greater appreciation of the importance of the gut microbiome to the health of the host …