Alzheimer's disease (AD) is a neurodegenerative old age disease that is complex,
multifactorial, unalterable, and progressive in nature. The currently approved therapy …

Heterocyclic compounds account for the most prominent and diverse class of organic
compounds. A significant number of heterocyclic compounds have been synthesized up to …

Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in
learning, memory, stress responses, and cognitive functioning. It is hydrolyzed into choline …

Abstract A new coumarin derivative, 7-((8-(4-benzylpiperidin-1-yl) octyl) oxy)-4-methyl-2H-
chromen-2-one (C3), was synthesized by two-step alkylation reaction of 7-hydroxy-4-methyl …

Alzheimer's disease (AD) is a neurological disorder that leads to dementia ie, progressive
memory loss accompanied with worsening of thinking ability of an individual. The cause of …

Introduction Alzheimer's disease is a multifactorial neurodegenerative disorder
characterized by beta-amyloid accumulation and tau protein hyperphosphorylation. The …

Introduction Alzheimer's disease (AD) is one of the most common and prevalent forms of
neurodegenerative diseases. Coumarin is a versatile scaffold that exhibits a wide range of …

Alzheimer's disease (AD) is one of the most prevalent geriatric diseases and a significant
cause of high mortality. This crippling disorder is becoming more prevalent at an …

Abstract Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are enzymes that
serve a wide range of physiological functions including the hydrolysis of the neurotransmitter …

The main feature of neurodegenerative diseases, including Alzheimer's disease, is the
network of complex and not fully recognized neuronal pathways and targets involved in their …