Peripheral artery disease (PAD) is the atherosclerosis of lower extremity arteries and is also
associated with atherothrombosis of other vascular beds, including the cardiovascular and …

Lower extremity amputation (LEA) in patients with diabetes results in high mortality, reduced
quality of life, and increased medical costs. Exact data on incidences of LEA in diabetic and …

Neuropathy and ischaemia are two great pathologies of the diabetic foot which lead to the
characteristic features of foot ulceration (neuropathic and ischaemic) and Charcot …

Critical limb ischemia, first defined in 1982, was intended to delineate a subgroup of patients
with a threatened lower extremity primarily because of chronic ischemia. It was the intent of …

Background Diabetes mellitus continues to grow in global prevalence and to consume an
increasing amount of health care resources. One of the key areas of morbidity associated …

Critical limb ischemia (CLI) is considered the most severe pattern of peripheral artery
disease. It is defined by the presence of chronic ischemic rest pain, ulceration or gangrene …

Diabetic foot ulcer is a devastating complication of diabetes mellitus and significant cause of
mortality and morbidity all over the world and can be complex and costly. The development …

OBJECTIVE Conflicting evidence exists on the effects of hyperbaric oxygen therapy (HBOT)
in the treatment of chronic ischemic leg ulcers. The aim of this trial was to investigate …

Diabetes mellitus is associated with a series of macrovascular and microvascular changes
that can manifest as a wide range of complications. Foot ulcerations affect∼ 2–4% of …

Symptoms or signs of peripheral artery disease (PAD) can be observed in up to 50% of the
patients with a diabetic foot ulcer and is a risk factor for poor healing and amputation. In …