Patients are exposed to numerous prescribed and over-the-counter medications.
Unfortunately, drugs remain a relatively common cause of acute and chronic kidney injury. A …

Drug-induced acute kidney injury: diverse mechanisms of tubu... : Current Opinion in Critical
Care Drug-induced acute kidney injury: diverse mechanisms of tubular injury : Current Opinion …

Despite dramatic improvements in patient survival and drug tolerability, nephrotoxicity
remains an important complication of chemotherapy. Adverse renal effects occur because of …

Drug-induced kidney disease occurs primarily in patients with underlying risk factors. A
number of factors enhance the vulnerability of the kidney to the nephrotoxic effects of drugs …

Nephrotoxicity remains a vexing complication of chemotherapeutic agents. A number of
kidney lesions can result from these drugs, including primarily tubular-limited dysfunction …

Melatonin is a neurohormone that is mainly secreted by the pineal gland. It coordinates the
work of the superior biological clock and consequently affects many processes in the human …

Background Drug-induced nephrotoxicity is a relatively common preventable cause of acute
kidney injury (AKI), providing early recognition and management. The pharmacokinetics or …

In this study, approximately 40 endogenous metabolites were identified and quantified by
1H NMR in urine samples from male rats dosed with two proximal tubule toxicants, cisplatin …

A variety of marketed drugs belonging to various therapeutic classes are known to cause
nephrotoxicity. Nephrotoxicity can manifest itself in several forms depending on the specific …

Polypharmacy, the concurrent use of multiple medicines, could increase the risk of kidney
dysfunction among older adults because it likely burdens the aging kidneys to excrete …