Plants as sources of natural and recombinant anti-cancer agents

JF Buyel - Biotechnology advances, 2018 - Elsevier
Herbal remedies were the first medicines used by humans due to the many
pharmacologically active secondary metabolites produced by plants. Some of these …

Molecular farming in plants: host systems and expression technology

RM Twyman, E Stoger, S Schillberg, P Christou… - TRENDS in …, 2003 - cell.com
Plants provide an inexpensive and convenient system for the large-scale production of
valuable recombinant proteins. This principle has been demonstrated by the commercial …

Retracted: An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus

O Voinnet, S Rivas, P Mestre, D Baulcombe - The plant journal, 2003 - Wiley Online Library
Transient gene expression is a fast, flexible and reproducible approach to high‐level
expression of useful proteins. In plants, recombinant strains of Agrobacterium tumefaciens …

Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules

SA Wilson, SC Roberts - Plant biotechnology journal, 2012 - Wiley Online Library
Plant cell culture systems were initially explored for use in commercial synthesis of several
high‐value secondary metabolites, allowing for sustainable production that was not limited …

Plant‐made vaccines for humans and animals

EP Rybicki - Plant biotechnology journal, 2010 - Wiley Online Library
The concept of using plants to produce high‐value pharmaceuticals such as vaccines is 20
years old this year and is only now on the brink of realisation as an established technology …

Of mice and men: hybridoma and recombinant antibodies

M Little, SM Kipriyanov, F Le Gall, G Moldenhauer - Immunology today, 2000 - cell.com
Thousands of mouse monoclonal antibodies have been produced from hybridomas over the
past 25 years. The same technique can now be used to clone human antibodies from …

Can the world's favorite fruit, tomato, provide an effective biosynthetic chassis for high-value metabolites?

Y Li, H Wang, Y Zhang, C Martin - Plant Cell Reports, 2018 - Springer
Tomato has a relatively short growth cycle (fruit ready to pick within 65–85 days from
planting) and a relatively high yield (the average for globe tomatoes is 3–9 kg fruit per plant …

Green factory: plants as bioproduction platforms for recombinant proteins

J Xu, MC Dolan, G Medrano, CL Cramer… - Biotechnology …, 2012 - Elsevier
Molecular farming, long considered a promising strategy to produce valuable recombinant
proteins not only for human and veterinary medicine, but also for agriculture and industry …

Plant-produced vaccines: promise and reality

EP Rybicki - Drug discovery today, 2009 - Elsevier
Plant-produced vaccines are a much-hyped development of the past two decades, whose
time to embrace reality may have finally come. Vaccines have been developed against viral …

[PDF][PDF] Optimization of transient Agrobacterium-mediated gene expression system in leaves of Nicotiana benthamiana

M Wydro, E Kozubek, P Lehmann - Acta biochimica polonica, 2006 - bibliotekanauki.pl
Here we report on a simple and reproducible system of Agrobacterium-mediated transient
gene expression assay that utilizes infiltration of young Nicotiana benthamiana leaves …