Protein lipidation is an important co-or posttranslational modification in which lipid moieties
are covalently attached to proteins. Lipidation markedly increases the hydrophobicity of …

The plasma membrane is of central importance for defining the closed volume of cells in
contradistinction to the extracellular environment. The plasma membrane not only serves as …

Various lipids and lipid metabolites are bound to and modify the proteins in eukaryotic cells,
which are known as 'protein lipidation'. There are four major types of the protein lipidation, ie …

The β2 adrenergic receptor (β2AR) signals through both Gs and Gi in cardiac myocytes, and
the Gi pathway counteracts the Gs pathway. However, Gi coupling is much less efficient than …

Membranes are mainly composed of a lipid bilayer and proteins, constituting a checkpoint
for the entry and passage of signals and other molecules. Their composition can be …

Our current understanding of membrane lipid composition, structure and functions has led to
the investigation of their role in cell signaling, both in healthy and pathological cells. As a …

Covalent attachment of C16: 0 to proteins (palmitoylation) regulates protein function.
Proteins are also S-acylated by other fatty acids including C18: 0. Whether protein acylation …

Lipid rafts formed by glycosphingolipids (GSLs) on cellular membranes play important roles
in innate and adaptive immunity. Lactosylceramide (LacCer) forms lipid rafts on plasma and …

Infectious diseases remain significant health concerns worldwide, and resistance is
particularly common in patients with tuberculosis caused by Mycobacterium tuberculosis …

Posttranslational modifications increase the complexity and functional diversity of proteins in
response to complex external stimuli and internal changes. Among these, protein lipidations …