Apoptosis or programmed cell death is natural way of removing aged cells from the body.
Most of the anti-cancer therapies trigger apoptosis induction and related cell death networks …

Immune dysregulation is a cardinal feature of chronic lymphocytic leukemia (CLL) from its
early stage and worsens during clinical observation, even in absence of disease …

The balance between immune effector cells such as T cells and natural killer cells, and
immunosuppressive Treg cells, dendritic, myeloid and monocytic sub-populations in the …

Fas-mediated apoptosis contributes to physiological and pathological cellular processes,
such as differentiation and survival. In particular, the roles of Fas in immune cells are …

Therapeutic monoclonal antibodies (mAbs) have become one of the fastest growing classes
of drugs in recent years and are approved for the treatment of a wide range of indications …

Secondary immunodeficiency is reported in most patients with hematological malignancies
such as chronic lymphocytic leukemia and multiple myeloma. The aim of our review was to …

To examine the impact of tumors on the immune system, we compared global gene
expression profiles of peripheral blood T cells from previously untreated patients with B cell …

Advances in understanding of the immune microenvironment have highlighted the role of
immunosuppressive T cell, myeloid, dendritic and monocytic sub-populations in inhibition of …

Thrombospondin forms a'molecular bridge'between phagocytic and apoptotic cells through
interaction with αvβ3/CD36. We report here that engagement of CD47, a newly described …

Chronic lymphocytic leukemia is frequently associated with immune disturbances. The
relationship between chronic lymphocytic leukemia and autoimmune cytopenias, particularly …