Could contact lens dryness discomfort symptoms sometimes have a neuropathic basis?

CW McMonnies - Eye and Vision, 2021 - Springer
Symptoms of dryness discomfort in soft contact lens wearers frequently lead to
discontinuation from wear. The negative influence of pre-fitting tear dysfunctions appears …

Generative adversarial network based automatic segmentation of corneal subbasal nerves on in vivo confocal microscopy images

E Yıldız, AT Arslan, AY Taş, AF Acer… - … Vision Science & …, 2021 - tvst.arvojournals.org
Purpose: In vivo confocal microscopy (IVCM) is a noninvasive, reproducible, and
inexpensive diagnostic tool for corneal diseases. However, widespread and effortless image …

Corneal confocal microscopy demonstrates axonal loss in different courses of multiple sclerosis

IN Petropoulos, KC Fitzgerald, J Oakley, G Ponirakis… - Scientific reports, 2021 - nature.com
Axonal loss is the main determinant of disease progression in multiple sclerosis (MS). This
study aimed to assess the utility of corneal confocal microscopy (CCM) in detecting corneal …

Visual dysfunction in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis: a review

T Shin, M Ahn, J Kim, K Jung, C Moon, MD Kim - Molecular Neurobiology, 2021 - Springer
Visual disabilities in central nervous system autoimmune diseases such as multiple
sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE) …

Corneal axonal loss as an imaging biomarker of neurodegeneration in multiple sclerosis: a longitudinal study

IN Petropoulos, F Al-Shibani… - Therapeutic …, 2023 - journals.sagepub.com
Background: Resourceful endpoints of axonal loss are needed to predict the course of
multiple sclerosis (MS). Corneal confocal microscopy (CCM) can detect axonal loss in …

Corneal immune cells as a biomarker of inflammation in multiple sclerosis: a longitudinal study

IN Petropoulos, K John, F Al-Shibani… - Therapeutic …, 2023 - journals.sagepub.com
Background: Corneal immune cells (ICs) are antigen-presenting cells that are known to
increase ocular and systemic inflammatory conditions. Objective: We aimed to assess …

Multi-scale and local feature guidance network for corneal nerve fiber segmentation

W Tang, X Chen, J Yuan, Q Meng, F Shi… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Corneal confocal microscopy (CCM) is a rapid and non-invasive ophthalmic
imaging technique that can reveal corneal nerve fiber. The automatic segmentation of …

[HTML][HTML] Corneal Confocal Microscopy Identifies and Differentiates Patients With Multiple Sclerosis and Epilepsy

IN Petropoulos, KE Aly, S Al-Thani… - … Vision Science & …, 2024 - iovs.arvojournals.org
Purpose: To assess whether corneal nerve analysis can identify and differentiate patients
with multiple sclerosis (MS) from those with epilepsy. Methods: Participants with MS (n= 83) …

Corneal epithelial dendritic cells in patients with multiple sclerosis: An in vivo confocal microscopy study

V Testa, N De Santis, R Scotto, P Della Giustina… - Journal of Clinical …, 2020 - Elsevier
Purpose To evaluate density and morphology of corneal epithelial dendritic cells (DCs) in
patients with multiple sclerosis (MS) using in vivo confocal microscopy (IVCM). Methods This …

In vivo confocal microscopy of corneal nerve fiber damage in early course of multiple sclerosis

M Toprak, O Altintas, H Bickin, H Efendi… - International …, 2023 - Springer
Purpose To evaluate the corneal nerve fiber morphology in patients with multiple sclerosis
(MS) by in vivo corneal confocal microscopy (CCM). Methods Retinal nerve fiber layer …