The Natural Biotic Environment of Caenorhabditis elegans

H Schulenburg, MA Félix - Genetics, 2017 - academic.oup.com
Organisms evolve in response to their natural environment. Consideration of natural
ecological parameters are thus of key importance for our understanding of an organism's …

Toll-like receptors, associated biological roles, and signaling networks in non-mammals

L Nie, SY Cai, JZ Shao, J Chen - Frontiers in immunology, 2018 - frontiersin.org
The innate immune system is the first line of defense against pathogens, which is initiated by
the recognition of pathogen-associated molecular patterns (PAMPs) and endogenous …

[HTML][HTML] Piwi/PRG-1 argonaute and TGF-β mediate transgenerational learned pathogenic avoidance

RS Moore, R Kaletsky, CT Murphy - Cell, 2019 - cell.com
The ability to inherit learned information from parents could be evolutionarily beneficial,
enabling progeny to better survive dangerous conditions. We discovered that, after C …

[HTML][HTML] Pathogen recognition and innate immunity

S Akira, S Uematsu, O Takeuchi - Cell, 2006 - cell.com
Microorganisms that invade a vertebrate host are initially recognized by the innate immune
system through germline-encoded pattern-recognition receptors (PRRs). Several classes of …

Microbes in gastrointestinal health and disease

AS Neish - Gastroenterology, 2009 - Elsevier
Most, if not all, animals coexist with a complement of prokaryotic symbionts that confer a
variety of physiologic benefits. In humans, the interaction between animal and bacterial cells …

Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans

Y Zhang, H Lu, CI Bargmann - Nature, 2005 - nature.com
Food can be hazardous, either through toxicity or through bacterial infections that follow the
ingestion of a tainted food source. Because learning about food quality enhances survival …

Are innate immune signaling pathways in plants and animals conserved?

FM Ausubel - Nature immunology, 2005 - nature.com
Although adaptive immunity is unique to vertebrates, the innate immune response seems to
have ancient origins. Common features of innate immunity in vertebrates, invertebrate …

The evolution of vertebrate Toll-like receptors

JC Roach, G Glusman, L Rowen… - Proceedings of the …, 2005 - National Acad Sciences
The complete sequences of Takifugu Toll-like receptor (TLR) loci and gene predictions from
many draft genomes enable comprehensive molecular phylogenetic analysis. Strong …

Evolution of protein kinase signaling from yeast to man

G Manning, GD Plowman, T Hunter… - Trends in biochemical …, 2002 - cell.com
Protein phosphorylation controls many cellular processes, especially those involved in
intercellular communication and coordination of complex functions. To explore the evolution …

Neuro-immune interactions at barrier surfaces

H Veiga-Fernandes, D Mucida - Cell, 2016 - cell.com
Multidirectional interactions between the nervous and immune systems have been
documented in homeostasis and pathologies ranging from multiple sclerosis to autism, and …