Despite the availability of over 30 antiseizure medications (ASMs), there is no “one size fits it
all,” so there is a continuing search for novel ASMs. There are divergent data demonstrating …

Epilepsy is a devastating neurological disorder characterized by recurrent seizures
attributed to the disruption of the dynamic excitatory and inhibitory balance in the brain …

Abstract The 5HT2BR, class-A GPCR is a new target, and its significance for seizure
reduction in Dravet syndrome is just now gaining interest, suggesting its specific role in …

Epilepsy is a common neurological disease characterized by distinct pathological changes
in the epileptogenic zone. Antiseizure drugs (ASDs) are widely used as the primary …

The study intends to repurpose FDA drugs and investigate the mechanism of (5HT 2B R)
activation by comprehending inter-residue interactions. The 5HT 2B R is a novel thread, and …

The central serotonin 2B receptor (5-HT 2B R) modulates 5-HT and dopamine (DA)
neuronal function in the mammalian brain and has been suggested as a potential target for …

Novelty detection, crucial to episodic memory formation, is impaired in epileptic patients with
mesial temporal lobe resection. Mismatch novelty detection, that activates the hippocampal …

Epilepsy is characterized by neuronal discharges that occur as a result of disruption of the
excitatory and inhibitory balance of the brain due to functional and structural changes. It has …

Results: Interleukin (IL)-6 levels were significantly increased in the male liver and kidney
tissues in both TBI groups compared to the control group but were seen to be decreased in …

Epilepsy is a complex and common neurological disorder characterized by spontaneous
and recurrent seizures, affecting~ 75 million individuals worldwide. Numerous studies have …