[HTML][HTML] Red blood cell storage lesion: causes and potential clinical consequences
T Yoshida, M Prudent, A D'Alessandro - Blood Transfusion, 2019 - ncbi.nlm.nih.gov
Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …
[HTML][HTML] Exosomal therapy—A new frontier in regenerative medicine
S Muthu, A Bapat, R Jain, N Jeyaraman… - Stem Cell …, 2021 - ncbi.nlm.nih.gov
The recent advances in translational and nanomedicine have paved the way for developing
the targeted drug delivery system at a greater pace among global researchers. On par with …
the targeted drug delivery system at a greater pace among global researchers. On par with …
Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …
cell types and participate in physiological and pathophysiological processes. EVs mediate …
Effect of short-term vs. long-term blood storage on mortality after transfusion
Background Randomized, controlled trials have suggested that the transfusion of blood after
prolonged storage does not increase the risk of adverse outcomes among patients, although …
prolonged storage does not increase the risk of adverse outcomes among patients, although …
Plasma membrane lipid domains as platforms for vesicle biogenesis and shedding?
H Pollet, L Conrard, AS Cloos, D Tyteca - Biomolecules, 2018 - mdpi.com
Extracellular vesicles (EVs) contribute to several pathophysiological processes and appear
as emerging targets for disease diagnosis and therapy. However, successful translation from …
as emerging targets for disease diagnosis and therapy. However, successful translation from …
Platelet microparticles: detection and assessment of their paradoxical functional roles in disease and regenerative medicine
There is increasing research on and clinical interest in the physiological role played by
platelet microparticles (PMPs). PMPs are 0.1–1-μm fragments shed from plasma …
platelet microparticles (PMPs). PMPs are 0.1–1-μm fragments shed from plasma …
Platelet inflammatory response to stress
Blood platelets play a central hemostatic role,(i) as they repair vascular epithelial damage,
and (ii) they play immune defense roles, as they have the capacity to produce and secrete …
and (ii) they play immune defense roles, as they have the capacity to produce and secrete …
An overview of the role of microparticles/microvesicles in blood components: are they clinically beneficial or harmful?
T Burnouf, ML Chou, H Goubran, F Cognasse… - … and Apheresis Science, 2015 - Elsevier
Blood cells and tissues generate heterogeneous populations of cell-derived vesicles,
ranging from approximately 50 nm to 1 µm in diameter. Under normal physiological …
ranging from approximately 50 nm to 1 µm in diameter. Under normal physiological …
Glucose 6-phosphate dehydrogenase deficient subjects may be better “storers” than donors of red blood cells
Storage of packed red blood cells (RBCs) is associated with progressive accumulation of
lesions, mostly triggered by energy and oxidative stresses, which potentially compromise the …
lesions, mostly triggered by energy and oxidative stresses, which potentially compromise the …
Red blood cell vesiculation in hereditary hemolytic anemia
A Alaarg, RM Schiffelers, WW van Solinge… - Frontiers in …, 2013 - frontiersin.org
Hereditary hemolytic anemia encompasses a heterogeneous group of anemias
characterized by decreased red blood cell survival because of inherited membrane …
characterized by decreased red blood cell survival because of inherited membrane …