[HTML][HTML] Pathophysiology of the effects of alcohol abuse on the endocrine system

N Rachdaoui, DK Sarkar - Alcohol research: current reviews, 2017 - ncbi.nlm.nih.gov
Alcohol can permeate virtually every organ and tissue in the body, resulting in tissue injury
and organ dysfunction. Considerable evidence indicates that alcohol abuse results in …

Association of prenatal alcohol exposure with offspring DNA methylation in mammals: a systematic review of the evidence

M Bestry, M Symons, A Larcombe, E Muggli… - Clinical …, 2022 - Springer
Background Prenatal alcohol exposure (PAE) is associated with a range of adverse
offspring neurodevelopmental outcomes. Several studies suggest that PAE modifies DNA …

Altered amygdala DNA methylation mechanisms after adolescent alcohol exposure contribute to adult anxiety and alcohol drinking

AJ Sakharkar, EJ Kyzar, DP Gavin, H Zhang, Y Chen… - …, 2019 - Elsevier
Binge drinking during adolescence increases the risk for neuropsychiatric disorders
including alcoholism in adulthood. DNA methylation in post-mitotic neurons is an important …

DNA methylation in alcohol use disorder

Q Zheng, H Wang, A Yan, F Yin, X Qiao - International Journal of …, 2023 - mdpi.com
Excessive drinking damages the central nervous system of individuals and can even cause
alcohol use disorder (AUD). AUD is regulated by both genetic and environmental factors …

Gestational alcohol exposure altered DNA methylation status in the developing fetus

C Mandal, D Halder, KH Jung, YG Chai - International journal of …, 2017 - mdpi.com
Ethanol is well known as a teratogenic factor that is capable of inducing a wide range of
developmental abnormalities if the developing fetus is exposed to it. Duration and dose are …

The effect of heavy prenatal alcohol exposure on adolescent body mass index and waist-to-height ratio at 12–13 years

N Hayes, N Reid, LK Akison, KM Moritz - International Journal of …, 2021 - nature.com
Background Growing evidence suggests that prenatal alcohol exposure (PAE) has the
potential to impact on a wide range of physical outcomes in offspring, including metabolism …

Sex-and tissue-specific effects of binge-level prenatal alcohol consumption on DNA methylation at birth

YJ Loke, E Muggli, R Saffery, J Ryan, S Lewis… - …, 2021 - Taylor & Francis
Background: Binge-level prenatal alcohol exposure (PAE) causes developmental
abnormalities, which may be mediated in part by epigenetic mechanisms. Despite this, few …

[HTML][HTML] In utero alcohol exposure and the alteration of histone marks in the developing fetus: an epigenetic phenomenon of maternal drinking

C Mandal, D Halder, KH Jung… - International Journal of …, 2017 - ncbi.nlm.nih.gov
Ethanol is well known for its teratogenic effects during fetal development. Maternal alcohol
consumption allows the developing fetus to experience the detrimental effects of alcohol …

Histone deacetylase 11 suppresses p53 expression in pituitary tumor cells

W Wang, L Fu, S Li, Z Xu, X Li - Cell Biology International, 2017 - Wiley Online Library
The pathogenesis of pituitary tumors (PT) is unclear. Deregulation of apoptosis is one of the
factors involving tumor growth. Histone deacetylases (HDAC) have an active role in multiple …

PRL/microRNA-183/IRS1 pathway regulates milk fat metabolism in cow mammary epithelial cells

P Jiao, Y Yuan, M Zhang, Y Sun, C Wei, X Xie, Y Zhang… - Genes, 2020 - mdpi.com
The aim of the study was to understand the internal relationship between milk quality and
lipid metabolism in cow mammary glands. A serial of studies was conducted to assess the …