A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

In addition to their classical roles as detergents to aid in the process of digestion, bile acids
have been identified as important signaling molecules that function through various nuclear …

Bile acids are best known as detergents involved in the digestion of lipids. In addition, new
data in the last decade have shown that bile acids also function as gut hormones capable of …

Albumin, the most abundant plasma protein, is among the most studied of all proteins, being
important from clinical monitoring, physiological, and therapeutic perspectives. This unique …

The use of animal models, particularly genetically modified mice, continues to play a critical
role in studying the relationship between bile acid metabolism and human liver disease …

By definition, a vitamin is a substance that must be obtained regularly from the diet. Vitamin
A must be acquired from the diet, but unlike most vitamins, it can also be stored within the …

Different from some more specialised short reviews, here a general although not
encyclopaedic survey of the function, metabolic role, structure and mechanism of the …

Bile acids (BA) are amphipathic steroid acids synthesized from cholesterol in the liver. They
act as detergents to expedite the digestion and absorption of dietary lipids and lipophilic …

Some time ago, I wrote a review entitled ''Uncoupling of respiration and phosphorylation''for
the wx book ''Frontier of Cellular Bioenergetics''1. In that Ž. paper I hypothesized that i the …

Long chain fatty acids (LCFAs) are an important energy substrate used by cardiac myocytes
and other cells, but the mechanism whereby these molecules cross the plasma membrane is …