An ultrasound-exclusive non-invasive computational diagnostic framework for personalized cardiology of aortic valve stenosis

N Bahadormanesh, B Tomka, M Kadem… - Medical Image …, 2023 - Elsevier
Aortic stenosis (AS) is an acute and chronic cardiovascular disease and If left untreated,
50% of these patients will die within two years of developing symptoms. AS is characterized …

Reducing long‐term mortality post transcatheter aortic valve replacement requires systemic differentiation of patient‐specific coronary hemodynamics

S Khodaei, L Garber, M Abdelkhalek… - Journal of the …, 2023 - Am Heart Assoc
Background Despite the proven benefits of transcatheter aortic valve replacement (TAVR)
and its recent expansion toward the whole risk spectrum, coronary artery disease is present …

Impact of TAVR on coronary artery hemodynamics using clinical measurements and image‐based patient‐specific in silico modeling

L Garber, S Khodaei, N Maftoon… - Scientific Reports, 2023 - nature.com
In recent years, transcatheter aortic valve replacement (TAVR) has become the leading
method for treating aortic stenosis. While the procedure has improved dramatically in the …

[HTML][HTML] Early detection of risk of neo-sinus blood stasis post-transcatheter aortic valve replacement using personalized hemodynamic analysis

S Khodaei, M Abdelkhalek, N Maftoon, A Emadi… - Structural Heart, 2023 - Elsevier
Background Despite the demonstrated benefits of transcatheter aortic valve replacement
(TAVR), subclinical leaflet thrombosis and hypoattenuated leaflet thickening are commonly …

A Doppler-exclusive non-invasive computational diagnostic framework for personalized transcatheter aortic valve replacement

N Bahadormanesh, B Tomka, M Abdelkhalek… - Scientific Reports, 2023 - nature.com
Given the associated risks with transcatheter aortic valve replacement (TAVR), it is crucial to
determine how the implant will affect the valve dynamics and cardiac function, and if TAVR …

Regional assessment of aortic valve calcification using topographic maps in contrast-enhanced CT: In-vivo sex and severity-based differences in calcific presentation

M Abdelkhalek, MA Daeian… - … Imaging in Medicine …, 2023 - pmc.ncbi.nlm.nih.gov
Background Procedural planning for transcatheter aortic valve replacement (TAVR) is
routinely performed using contrast computed tomography (CT) in patients with severe aortic …

An interactive dose optimizer based on population pharmacokinetic study to guide dosing of methotrexate in Chinese patients with osteosarcoma

Y Zhang, X Qi, X Huang, X Liu, Y Liu, J Rui… - Cancer Chemotherapy …, 2024 - Springer
Purpose Osteosarcoma is a rare tumor with an incidence of 4.4 cases per million per year in
adolescent. High-dose methotrexate (HD-MTX) is the standard first-line chemotherapeutic …

Incremental prognostic value of intensity-weighted regional calcification scoring using contrast CT imaging in TAVR

M Abdelkhalek, N Bahadormanesh… - European Heart …, 2023 - academic.oup.com
Aims Aortic valve calcification scoring plays an important role in predicting outcomes of
transcatheter aortic valve replacement (TAVR). However, the impact of relative calcific …

A multi-domain lattice Boltzmann mesh refinement method for non-Newtonian blood flow modeling

MA Daeian, WS Smith, Z Keshavarz-Motamed - Physics of Fluids, 2025 - pubs.aip.org
a) Authors to whom correspondence should be addressed:[email protected]. URL:
https://www. eng. mcmaster. ca/cas/faculty/dr-spencer-smith/; https://www. cas. mcmaster …

Quantification of aortic valve calcification in contrast-enhanced computed tomography

D Laohachewin, P Ruile, P Breitbart, J Minners… - Journal of clinical …, 2024 - mdpi.com
Background: The goal of our study is to evaluate a method to quantify aortic valve
calcification (AVC) in contrast-enhanced computed tomography for patients with suspected …