Deep eutectic solvents (DESs) are the new class of green and inexpensive anhydrous
solvents, which are alternatives of ionic liquids. The applications of these promising …

Urea at sufficiently high concentration unfolds the secondary structure of proteins leading to
denaturation. In contrast, choline chloride (ChCl) and urea, in 1: 2 molar ratio, form a deep …

Quasi-ice-like hydration waters on the ice-binding surface (IBS) of an antifreeze protein
(AFP) commonly exhibit sluggish dynamics especially at low temperatures. In this work, we …

Formation of protein–DNA complex is an important step in regulation of genes in living
organisms. One important issue in this problem is the role played by water in mediating the …

Since the time of Kirkwood, observed deviations in magnitude of the dielectric constant of
aqueous protein solution from that of neat water (∼ 80) and slower decay of polarization …

Atomistic molecular dynamics simulations are used to probe changes in the nature and
subnanosecond dynamical behavior of solvation waters that accompany partial denaturation …

The breaking of the native structure of a protein and its influences on the dynamic response
of the surrounding solvent is an important issue in protein folding. In this work, we have …

The conformational flexibility of a protein and its ability to form hydrogen bonds with water
are expected to influence the microscopic properties of water layer hydrating the protein …

The thyroid hormone receptors (TR) are members of the nuclear receptor superfamily that
regulate growth, development, and metabolic processes in a ligand-dependent manner …

It is commonly assumed that the structure of water at a lipid-water interface is influenced
mostly in the first hydration layer. However, recent results from different experimental …