Tremendous progress has been made over the last ten years on East Coast fever (ECF)
research. Publication of a reference genome sequence of Theileria parva, the causative …

The genus Theileria includes tick-transmitted apicomplexan parasites of ruminants with
substantial economic impact in endemic countries. Some species, including Theileria parva …

Babesia bovis is an apicomplexan tick-transmitted pathogen of cattle imposing a global risk
and severe constraints to livestock health and economic development. The complete …

Intracellular pathogens have evolved a wide array of mechanisms to invade and co-opt their
host cells for intracellular survival. Apicomplexan parasites such as Toxoplasma gondii …

Background Transmission of arthropod-borne apicomplexan parasites that cause disease
and result in death or persistent infection represents a major challenge to global human and …

Maintaining genome integrity and transmission of intact genomes is critical for cellular,
organismal, and species survival. Cells can detect damaged DNA, activate checkpoints, and …

Tick-borne diseases (TBDs) affect 80% of the world's cattle population, hampering livestock
production throughout the world. Livestock industry is important to rural populations not only …

Toxoplasma gondii is an obligate intracellular parasite that causes severe disease in
humans. It is able to infect all nucleated mammalian cells leading to lifelong persistence of …

The modulation of apoptosis has emerged as an important weapon in the pathogenic
arsenal of multiple intracellular protozoan parasites. Cryptosporidium parvum, Leishmania …

Protein phosphorylation plays a fundamental role in the biology of apicomplexan parasites.
Many apicomplexan protein kinases are substantially different from their mammalian …