The transport of specific molecules across lipid membranes is an essential function of all
living organisms. The processes are usually mediated by specific transporters. One of the …

Type 2 diabetes (T2D) is a multifactorial anomaly involving 57 genes located on 16 different
chromosomes and 136 single nucleotide polymorphisms (SNPs). Ten genes are located on …

Background The rapid accumulation of single-cell RNA sequencing (scRNA-seq) data
presents unique opportunities to decode the genetically mediated cell-type specificity in …

The ABCC9 gene and its polypeptide product, SUR2, are increasingly implicated in human
neurologic disease, including prevalent diseases of the aged brain. SUR2 proteins are a …

Maturity-onset diabetes of the young (MODY) is a heterogeneous group of diseases
associated with gene mutations leading to dysfunction of pancreatic β-cells. Thirteen …

Monogenic diabetes is characterized as a group of diseases caused by rare variants in
single genes. Like for other rare diseases, multiple genes have been linked to monogenic …

Abstract Background Maturity Onset Diabetes of the Young (MODY) constitutes a genetically
and clinically heterogeneous type of monogenic diabetes. It is characterized by early onset …

Monogenic diabetes is a genetic disorder caused by one or more variations in a single
gene. It encompasses a broad spectrum of heterogeneous conditions, including neonatal …

Objectives. Diabetes mellitus (DM) is a major chronic metabolic disease in the world, and
the prevalence has been increasing rapidly in recent years. The channel of KATP plays an …

Prognostic significance and molecular mechanisms of adenosin... : Medicine Prognostic
significance and molecular mechanisms of adenosine triphosphate-binding cassette subfamily …