Central nervous system pericytes in health and disease
EA Winkler, RD Bell, BV Zlokovic - Nature neuroscience, 2011 - nature.com
Pericytes are uniquely positioned within the neurovascular unit to serve as vital integrators,
coordinators and effectors of many neurovascular functions, including angiogenesis, blood …
coordinators and effectors of many neurovascular functions, including angiogenesis, blood …
Vascular smooth muscle progenitor cells: building and repairing blood vessels
MW Majesky, XR Dong, JN Regan… - Circulation research, 2011 - Am Heart Assoc
Molecular pathways that control the specification, migration, and number of available
smooth muscle progenitor cells play key roles in determining blood vessel size and …
smooth muscle progenitor cells play key roles in determining blood vessel size and …
Tissue engineering using vascular organoids from human pluripotent stem cell derived mural cell phenotypes
M Markou, D Kouroupis, F Badounas… - … in bioengineering and …, 2020 - frontiersin.org
Diffusion is a limiting factor in regenerating large tissues (100–200 μm) due to reduced
nutrient supply and waste removal leading to low viability of the regenerating cells as …
nutrient supply and waste removal leading to low viability of the regenerating cells as …
Three-dimensional cell aggregates composed of HUVECs and cbMSCs for therapeutic neovascularization in a mouse model of hindlimb ischemia
The proximity of cells in three-dimensional (3D) organization maximizes the cell–cell
communication and signaling that are critical for cell function. In this study, 3D cell …
communication and signaling that are critical for cell function. In this study, 3D cell …
Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme
N El Hindy, K Keyvani, A Pagenstecher… - Neuro …, 2013 - academic.oup.com
Background Glioblastoma multiforme (GBM) is a highly aggressive brain tumor
characterized by massive neovascularization, necrosis, and intense resistance to therapy …
characterized by massive neovascularization, necrosis, and intense resistance to therapy …
Anti-DLL4, a cancer therapeutic with multiple mechanisms of action
A Gurney, T Hoey - Vascular cell, 2011 - Springer
DLL4 is a ligand for the Notch family of receptors. DLL4 has many important functions in
normal development and tissue homeostasis, including roles in the immune system, the …
normal development and tissue homeostasis, including roles in the immune system, the …
The role of endothelial cell-bound Jagged1 in Notch3-induced human coronary artery smooth muscle cell differentiation
Y Xia, A Bhattacharyya, EE Roszell, M Sandig… - Biomaterials, 2012 - Elsevier
Phenotype regulation of vascular smooth muscle cells (VSMC) is an important requirement
in both tissue engineering and balloon angioplasty strategies. In recent years, it has become …
in both tissue engineering and balloon angioplasty strategies. In recent years, it has become …
The evolving roles of pericyte in early brain injury after subarachnoid hemorrhage
Y Chen, Q Li, J Tang, H Feng, JH Zhang - Brain research, 2015 - Elsevier
Despite accumulated understanding on the mechanisms of early brain injury and improved
management of subarachnoid hemorrhage (SAH), it is still one of the serious and refractory …
management of subarachnoid hemorrhage (SAH), it is still one of the serious and refractory …
Delivery of a cell patch of cocultured endothelial cells and smooth muscle cells using thermoresponsive hydrogels for enhanced angiogenesis
Cell-based therapy has been studied as an attractive strategy for therapeutic angiogenesis.
However, obtaining a stable vascular structure remains a challenge due to the poor …
However, obtaining a stable vascular structure remains a challenge due to the poor …