Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases

L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Adipocytokines in relation to cardiovascular disease

J Van de Voorde, B Pauwels, C Boydens, K Decaluwé - Metabolism, 2013 - Elsevier
Adipose tissue can be considered as a huge gland producing paracrine and endocrine
hormones, the adipo (cyto) kines. There is growing evidence that these adipo (cyto) kines …

Adipokines and inflammation: focus on cardiovascular diseases

S Feijóo-Bandín, A Aragón-Herrera… - International journal of …, 2020 - mdpi.com
It is well established that adipose tissue, apart from its energy storage function, acts as an
endocrine organ that produces and secretes a number of bioactive substances, including …

Adipose tissue‐derived omentin‐1 function and regulation

T Watanabe, K Watanabe‐Kominato… - Comprehensive …, 2011 - Wiley Online Library
Omentin‐1, also known as intelectin‐1, is a recently identified novel adipocytokine of 313
amino acids, which is expressed in visceral (omental and epicardial) fat as well as …

Fat-derived factor omentin stimulates endothelial cell function and ischemia-induced revascularization via endothelial nitric oxide synthase-dependent mechanism

S Maruyama, R Shibata, R Kikuchi, Y Izumiya… - Journal of Biological …, 2012 - ASBMB
Obesity-related diseases are associated with vascular dysfunction and impaired
revascularization. Omentin is a fat-derived secreted protein, which is down-regulated in …

Circulating omentin is associated with coronary artery disease in men

R Shibata, N Ouchi, R Kikuchi, R Takahashi… - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: Obesity is closely associated with an increased risk for cardiovascular
morbidity and mortality. Omentin is a fat-derived secreted factor that is downregulated in …

Counteractive effects of omentin-1 against atherogenesis

K Watanabe, R Watanabe, H Konii… - Cardiovascular …, 2016 - academic.oup.com
Aims Omentin-1, a novel adipocytokine expressed in visceral fat tissue, is negatively
correlated with obesity, insulin resistance, and stable coronary artery disease (CAD) …

Association of circulating omentin-1 level with arterial stiffness and carotid plaque in type 2 diabetes

HJ Yoo, SY Hwang, HC Hong, HY Choi… - Cardiovascular …, 2011 - Springer
Background Adipokines contribute directly to the atherosclerotic process, connecting
metabolic disorders such as obesity and diabetes to cardiovascular disease. Omentin-1 is a …

Omentin: linking metabolic syndrome and cardiovascular disease

JY Zhou, L Chan, SW Zhou - Current vascular pharmacology, 2014 - ingentaconnect.com
Omentin is an adipokine preferentially produced by visceral adipose tissue with insulin-
sensitizing effects. Its expression is reduced in obesity, insulin resistance and type 2 …

Bifidobacterium pseudocatenulatum CECT 7765 supplementation improves inflammatory status in insulin-resistant obese children

J Sanchis-Chordà, EMG Del Pulgar… - European journal of …, 2019 - Springer
Purpose The relationships between gut microbiota and obesity-related co-morbidities have
been increasingly recognized. Low-grade inflammation may be the main factor in the …