Beyond polydimethylsiloxane: alternative materials for fabrication of organ-on-a-chip devices and microphysiological systems

SB Campbell, Q Wu, J Yazbeck, C Liu… - ACS biomaterials …, 2020 - ACS Publications
Polydimethylsiloxane (PDMS) is the predominant material used for organ-on-a-chip devices
and microphysiological systems (MPSs) due to its ease-of-use, elasticity, optical …

Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections

LM Ney, M Wipplinger, M Grossmann… - Open …, 2023 - royalsocietypublishing.org
The human intestinal microbiome substantially affects human health and resistance to
infections in its dynamic composition and varying release of microbial-derived metabolites …

A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip

S Jalili-Firoozinezhad, FS Gazzaniga… - Nature biomedical …, 2019 - nature.com
The diverse bacterial populations that comprise the commensal microbiome of the human
intestine play a central role in health and disease. A method that sustains complex microbial …

Organoid-based models to study the role of host-microbiota interactions in IBD

M Poletti, K Arnauts, M Ferrante… - Journal of Crohn's and …, 2021 - academic.oup.com
The gut microbiota appears to play a central role in health, and alterations in the gut
microbiota are observed in both forms of inflammatory bowel disease [IBD], namely Crohn's …

Islam and International Standards of Human Rights: An Analysis of Domestic Implementation of International Human Rights in Islamic Culture

N Hussain, W Xi - Assyfa Journal of Islamic Studies, 2023 - journal.assyfa.com
The understanding of human rights concepts and laws has developed dramatically. Human
rights concepts have shaped the moral, ethical, legal, political, and religious realities of …

Gut microbiota and Alzheimer's disease: how to study and apply their relationship

NM Nguyen, J Cho, C Lee - International journal of molecular sciences, 2023 - mdpi.com
Gut microbiota (GM), the microorganisms in the gastrointestinal tract, contribute to the
regulation of brain homeostasis through bidirectional communication between the gut and …

Recent advances in microfluidic technology for manipulation and analysis of biological cells (2007–2017)

MK Alam, E Koomson, H Zou, C Yi, CW Li, T Xu… - Analytica chimica …, 2018 - Elsevier
The pivotal role of microfluidic technology in life science and biomedical research is now
widely recognized. Indeed, microfluidics as a research tool is unparalleled in terms of its …

Flat and microstructured polymeric membranes in organs-on-chips

T Pasman, D Grijpma… - Journal of the Royal …, 2018 - royalsocietypublishing.org
In recent years, organs-on-chips (OOCs) have been developed to meet the desire for more
realistic in vitro cell culture models. These systems introduce microfluidics, mechanical …

[HTML][HTML] Gut-on-Chip microphysiological systems: Latest advances in the integration of sensing strategies and adoption of mature detection mechanisms

MA Signore, C De Pascali, L Giampetruzzi… - Sensing and Bio …, 2021 - Elsevier
Synergic efforts in microfabrication processes, cells culture and tissue engineering promoted
extraordinary progress in Organ-on-Chip (OoC) technology, leading to the development of in …

Relevance of organ (s)-on-a-chip systems to the investigation of food-gut microbiota-host interactions

E Garcia-Gutierrez, PD Cotter - Critical Reviews in Microbiology, 2022 - Taylor & Francis
The ever greater understanding of the composition and function of the gut microbiome has
provided new opportunities with respect to understanding and treating human disease …