Obesogens: How they are identified and molecular mechanisms underlying their action
N Mohajer, CY Du, C Checkcinco… - Frontiers in …, 2021 - frontiersin.org
Adult and childhood obesity have reached pandemic level proportions. The idea that caloric
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …
Consensus on the key characteristics of metabolism disruptors
MA La Merrill, MT Smith, CM McHale… - Nature Reviews …, 2024 - nature.com
Metabolism-disrupting agents (MDAs) are chemical, infectious or physical agents that
increase the risk of metabolic disorders. Examples include pharmaceuticals, such as …
increase the risk of metabolic disorders. Examples include pharmaceuticals, such as …
[HTML][HTML] Prenatal exposures to mixtures of endocrine disrupting chemicals and sex-specific associations with children's BMI and overweight at 5.5 years of age in the …
K Svensson, C Gennings, C Lindh, H Kiviranta… - Environment …, 2023 - Elsevier
Background Prenatal exposure to mixtures of endocrine disrupting chemicals (EDC) has the
potential to disrupt human metabolism. Prenatal periods are especially sensitive as many …
potential to disrupt human metabolism. Prenatal periods are especially sensitive as many …
Perinatal triphenyl phosphate exposure induces metabolic dysfunctions through the EGFR/ERK/AKT signaling pathway: Mechanistic in vitro and in vivo studies
P Tachachartvanich, X Rusit, J Tong, C Mann… - Ecotoxicology and …, 2024 - Elsevier
Triphenyl phosphate (TPhP), a widely used organophosphate-flame retardant, is
ubiquitously found in household environments and may adversely affect human health …
ubiquitously found in household environments and may adversely affect human health …
Effects of endocrine disruptors on the electrical activity of leptin receptor neurons in the dorsomedial hypothalamus and anxiety-like behavior in male mice
There is increasing concern about the effects of endocrine disrupting chemicals (EDCs) on
human health. Recently, some EDCs are suggested to affect energy metabolism leading to …
human health. Recently, some EDCs are suggested to affect energy metabolism leading to …
[HTML][HTML] Potential obesogenic effect of a complex contaminant mixture on Cree First Nations adults of Northern Québec, Canada
Background Obesity incidence and prevalence is of increasing concern in First Nations
communities around Canada. In addition to diet and physical activity, environmental …
communities around Canada. In addition to diet and physical activity, environmental …
[HTML][HTML] Morphological study of neuropeptide Y expression in human and mouse anterior insular cortex: Overexpression in the insular cortex and nucleus accumbens …
L Santana-Cordón, D Afonso-Oramas… - Annals of Anatomy …, 2023 - Elsevier
Background The anterior lobe of the insular cortex (aINS) is a cortical region that has
reciprocal connections with limbic centers such as the anterior cingulate cortex, prefrontal …
reciprocal connections with limbic centers such as the anterior cingulate cortex, prefrontal …
[HTML][HTML] Adaptation of Brown Adipose Tissue in Response to Chronic Exposure to the Environmental Pollutant 1, 1-Dichloro-2, 2-bis (p-chlorophenyl) Ethylene (DDE) …
V Migliaccio, I Di Gregorio, S Penna, G Panico… - Nutrients, 2024 - mdpi.com
Brown adipose tissue (BAT) participates in thermogenesis and energy homeostasis. Studies
on factors capable of influencing BAT function, such as a high-fat diet (HFD) or exposure to …
on factors capable of influencing BAT function, such as a high-fat diet (HFD) or exposure to …
Impaired energy expenditure following exposure to either DDT or DDE in mice may be mediated by DNA methylation changes in brown adipose
JA Jugan, KB Jackson, SE Elmore… - Environmental …, 2024 - academic.oup.com
The insecticide dichlorodiphenyltrichloroethane (DDT) and its persistent metabolite,
dichlorodiphenyldichloroethylene (DDE), have been associated with increased adiposity …
dichlorodiphenyldichloroethylene (DDE), have been associated with increased adiposity …
Role of nutraceutical against exposure to pesticide residues: power of bioactive compounds
Pesticides play a crucial role in modern agriculture, aiding in the protection of crops from
pests and diseases. However, their indiscriminate use has raised concerns about their …
pests and diseases. However, their indiscriminate use has raised concerns about their …