The roles of subcellularly located EGFR in autophagy
H Li, L You, J Xie, H Pan, W Han - Cellular signalling, 2017 - Elsevier
The epidermal growth factor receptor (EGFR) is a well-studied receptor-tyrosine kinase that
serves vital roles in regulation of organ development and cancer progression. EGFR not …
serves vital roles in regulation of organ development and cancer progression. EGFR not …
[HTML][HTML] Multiple mutations in the EGFR gene in lung cancer: a systematic review
JP Castañeda-González, JJ Chaves… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Background Lung cancer is a public health problem worldwide. Currently, identifying genetic
mutations in the epidermal growth factor receptor (EGFR) has brought significant changes in …
mutations in the epidermal growth factor receptor (EGFR) has brought significant changes in …
Dynamic conformational transitions of the EGF receptor in living mammalian cells determined by FRET and fluorescence lifetime imaging microscopy
I Ziomkiewicz, A Loman, R Klement, C Fritsch… - Cytometry Part …, 2013 - Wiley Online Library
We have revealed a reorientation of ectodomain I of the epidermal growth factor receptor
(EGFR; ErbB1; Her1) in living CHO cells expressing the receptor, upon binding of the native …
(EGFR; ErbB1; Her1) in living CHO cells expressing the receptor, upon binding of the native …
Structures of the EphA2 receptor at the membrane: role of lipid interactions
Ephs are transmembrane receptors that mediate cell-cell signaling. The N-terminal
ectodomain binds ligands and enables receptor clustering, which activates the intracellular …
ectodomain binds ligands and enables receptor clustering, which activates the intracellular …
Exploring the dynamics and interaction of a full ErbB2 receptor and Trastuzumab-Fab antibody in a lipid bilayer model using Martini coarse-grained force field
Coarse grained (CG) modeling has been applied to study the influence of the Trastuzumab
monoclonal antibody on the structure and dynamics of the full ErbB2 receptor dimer …
monoclonal antibody on the structure and dynamics of the full ErbB2 receptor dimer …
[PDF][PDF] Molecular analysis of EGFR gene in different types of tumor material from NSCLC patients
Lung carcinoma is the most frequently occurring cancer worldwide and the Non-small Cell
Lung Cancer (NSCLC) subtype represents 80% of all diagnosed cases. Epidermal growth …
Lung Cancer (NSCLC) subtype represents 80% of all diagnosed cases. Epidermal growth …
[PDF][PDF] Multiple mutations in the EGFR gene in lung cancer: a systematic
Background: Lung cancer is a public health problem worldwide. Currently, identifying
genetic mutations in the epidermal growth factor receptor (EGFR) has brought significant …
genetic mutations in the epidermal growth factor receptor (EGFR) has brought significant …
Microscopy techniques
A Feola, L Cito, A Di Carlo, A Giovane… - … Imaging Techniques in …, 2016 - Springer
The microscope is certainly the first equipment that was used by biologists; its invention
dates back 400 years, and it has remained an essential tool in biomedical research. Over …
dates back 400 years, and it has remained an essential tool in biomedical research. Over …
Emerging Molecular Targets in the Treatment of Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinoma (HNSCC) remains an important public health
problem in the USA and worldwide. Existing treatments involve surgery for early cancers …
problem in the USA and worldwide. Existing treatments involve surgery for early cancers …
[PDF][PDF] Protein–Protein Interactions in Epidermal Growth Factor Receptors Through Molecular Dynamics
JF Franco-Gonzalez, VL Cruz - 2015 - researchgate.net
The family of epidermal growth factor receptors (EGFR) is composed by four members:
EGFR/ErbB1, ErbB2, ErbB3 and ErbB4. They are associated with a number of biological …
EGFR/ErbB1, ErbB2, ErbB3 and ErbB4. They are associated with a number of biological …