In mammals, the expression of a subset of microRNA (miRNA) genes is governed by
genomic imprinting, an epigenetic mechanism that confers monoallelic expression in a …

Cancer ranks as the second leading cause of death worldwide, causing a large social and
economic burden. However, most anti-cancer treatments face the problems of tumor …

Recent studies have revealed that feed-forward loops (FFLs) as regulatory motifs have
synergistic roles in cellular systems and their disruption may cause diseases including …

Preeclampsia (PE) is a common cause of maternal morbidity, characterized by impaired
trophoblast invasion and spiral artery transformation resulting in progressive uteroplacental …

Extracellular vesicles (EVs) are reported to be involved in stem cell maintenance, self-
renewal, and differentiation. Due to their bioactive cargoes influencing cell fate and function …

Members of the placenta-specific miRNA cluster C19MC, including miR-519d, are secreted
by fetal trophoblast cells within extracellular vesicles (EVs). Trophoblast-derived EVs can be …

Aim: To understand miRNA changes across gestation in healthy human placentae. This is
essential before miRNAs can be used as biomarkers or prognostic indicators during …

Oral squamous cell carcinoma (OSCC) is among the leading causes of cancer-associated
deaths worldwide. Family members in miR-371/372/373 miRNA cluster, which is localized at …

Transposable element (TE) has the ability to insert into certain parts of the genome, and due
to this event, it is possible for TEs to generate new factors and one of these factors are …

Pluripotent stem cells have great potential for developmental biology and regenerative
medicine. Embryonic stem cells, which are obtained from blastocysts, and induced …