Steroidal saponins: naturally occurring compounds as inhibitors of the hallmarks of cancer
S Bouabdallah, A Al-Maktoum, A Amin - Cancers, 2023 - mdpi.com
Simple Summary Cancer is one of the most life-threatening diseases that affects a rapidly
growing number of individuals worldwide. Currently, chemotherapy is the most common …
growing number of individuals worldwide. Currently, chemotherapy is the most common …
A toxic shrub turned therapeutic: The dichotomy of Nerium oleander bioactivities
Nerium oleander L. is a medicinal plant, used for the treatment of cancers and
hyperglycemia across the world, especially in Indian sub-continent, Turkey, Morocco, and …
hyperglycemia across the world, especially in Indian sub-continent, Turkey, Morocco, and …
Differential activities of the botanical extract PBI-05204 and oleandrin on innate immune functions under viral challenge versus inflammatory culture conditions
GS Jensen, L Yu, I Iloba, D Cruickshank, JR Matos… - Molecules, 2023 - mdpi.com
The Nerium oleander extract PBI 05204 (PBI) and its cardiac glycoside constituent oleandrin
have direct anti-viral properties. Their effect on the immune system, however, is largely …
have direct anti-viral properties. Their effect on the immune system, however, is largely …
Investigation of the TLR4 and IRF3 signaling pathway-mediated effects of monensin in colorectal cancer cells
M Seçme, SS Kocoglu - Medical Oncology, 2023 - Springer
Monensin is an ionophore antibiotic isolated from Streptomyces cinnamonensis with very
strong antibacterial and antiparasitic effects. Although monensin is known to exhibit …
strong antibacterial and antiparasitic effects. Although monensin is known to exhibit …
Oleander attenuates hepatic inflammation in a TLR4-independent manner and by favorable modulation of hepatocellular global metabolome that supports …
Ethnopharmacological relevance Nerium oleander is used to treat liver-associated chronic
metabolic diseases in traditional medicinal systems across the globe. The hepatoprotective …
metabolic diseases in traditional medicinal systems across the globe. The hepatoprotective …
[PDF][PDF] Fusaric acid inhibits cell proliferation and downregulates expressions of toll-like receptors pathway genes in Ishikawa endometrial cancer cells.
OBJECTIVE: Fusaric acid is a derivative of picolinic acid produced by some Fusarium
species. In this study, we aimed to determine the mRNA expression and antiproliferative …
species. In this study, we aimed to determine the mRNA expression and antiproliferative …
Effects of Betulinic Acid in SK-UT-1leiomyosarcoma Cells on Cytotoxicity and TLR4-Myd88 Gene Expression
M Seçme, T Kerimova, R Mammadov… - … Conference on Smart …, 2024 - Springer
In this study, we detected the effects of betulinic acid (BA) on SKUT-1 leiomyosarcoma cells
regarding cytotoxicity and the expression of TLR4-MyD88 genes. We observed a dose-and …
regarding cytotoxicity and the expression of TLR4-MyD88 genes. We observed a dose-and …
Effects of Betulinic Acid in SK-UT-1leiomyosarcoma Cells on Cytotoxicity and TLR4-Myd88 Gene
M Seçme¹, T Kerimova, R Mammadov - International Conference on … - books.google.com
In this study, we detected the effects of betulinic acid (BA) on SKUT-1 leiomyosarcoma cells
regarding cytotoxicity and the expression of TLR4-MyD88 genes. We observed a dose-and …
regarding cytotoxicity and the expression of TLR4-MyD88 genes. We observed a dose-and …