The EBJIS definition of periprosthetic joint infection: a practical guide for clinicians

M McNally, R Sousa… - The bone & joint …, 2021 - boneandjoint.org.uk
Aims The diagnosis of periprosthetic joint infection (PJI) can be difficult. All current
diagnostic tests have problems with accuracy and interpretation of results. Many new tests …

Next generation sequencing for pathogen detection in periprosthetic joint infections

PF Indelli, S Ghirardelli, B Violante… - EFORT Open …, 2021 - eor.bioscientifica.com
Periprosthetic joint infections (PJI) represent one of the most catastrophic complications
following total joint arthroplasty (TJA). The lack of standardized diagnostic tests and …

Advances in the microbiological diagnosis of prosthetic joint infections

ME Portillo, I Sancho - Diagnostics, 2023 - mdpi.com
A significant number of prosthetic joint infections (PJI) are culture-negative and/or
misinterpreted as aseptic failures in spite of the correct implementation of diagnostic culture …

Direct detection and identification of periprosthetic joint infection pathogens by metagenomic next-generation sequencing

L Hao, P Wen, W Song, B Zhang, Y Wu, Y Zhang… - Scientific Reports, 2023 - nature.com
This study assessed the application of metagenomic next-generation sequencing in
pathogen detection of periprosthetic joint infections. A total of 95 cases who previously had …

The Microbiome of Peri-Implantitis: A Systematic Review of Next-Generation Sequencing Studies

K Chun Giok, RK Menon - Antibiotics, 2023 - mdpi.com
(1) Introduction: Current evidence shows that mechanical debridement augmented with
systemic and topical antibiotics may be beneficial for the treatment of peri-implantitis. The …

Joint aspiration for diagnosis of chronic periprosthetic joint infection: when, how, and what tests?

ND Quinlan, JM Jennings - Arthroplasty, 2023 - Springer
Diagnosing chronic periprosthetic joint infection (PJI) requires clinical suspicion in
combination with both serological and synovial fluid tests, the results of which are generally …

Principles of mechanical and chemical debridement with implant retention

DG Deckey, ZK Christopher, JS Bingham, MJ Spangehl - Arthroplasty, 2023 - Springer
Background Periprosthetic joint infection (PJI) is one of the most common causes of early
revision for total hip and knee arthroplasty. Mechanical and chemical debridement typically …

Comparison of microbial detection rates in microbial culture methods versus next-generation sequencing in patients with prosthetic joint infection: a systematic review …

H Kato, M Hagihara, N Asai, T Umemura, J Hirai… - Journal of Orthopaedic …, 2023 - Springer
Background Accurate diagnosis of prosthetic joint infection (PJI) enables early and effective
treatment. However, there is currently no gold standard test for microbial detection of PJI and …

Universal screening for malnutrition prior to total knee arthroplasty is cost-effective: a Markov analysis

MT Torchia, IA Khan, DD Christensen… - The Journal of …, 2023 - Elsevier
Background Patients undergoing total knee arthroplasty (TKA) who have malnutrition
possess an increased risk of periprosthetic joint infection (PJI). Although malnutrition …

Culture-Negative Streptococcus suis Infection Diagnosed by Metagenomic Next-Generation Sequencing

Y Dai, L Chen, W Chang, H Lu, P Cui… - Frontiers in public health, 2019 - frontiersin.org
Background: Streptococcus suis is a zoonotic pathogen that can cause severe infections
such as meningitis and septicemia in both swine and humans. Rapid and accurate …