The goldmine of GWAS summary statistics: a systematic review of methods and tools
Genome-wide association studies (GWAS) have revolutionized our understanding of the
genetic architecture of complex traits and diseases. GWAS summary statistics have become …
genetic architecture of complex traits and diseases. GWAS summary statistics have become …
Leveraging gene co-regulation to identify gene sets enriched for disease heritability
Identifying gene sets that are associated to disease can provide valuable biological
knowledge, but a fundamental challenge of gene set analyses of GWAS data is linking …
knowledge, but a fundamental challenge of gene set analyses of GWAS data is linking …
[图书][B] Improving understanding of complex diseases genetics with Bayesian sparse models and variational inference
W Zhang - 2023 - search.proquest.com
Large biobanks and advanced sequencing technologies have enabled large-scale GWAS,
yielding numerous associations between genetic variants and complex diseases. GWAS …
yielding numerous associations between genetic variants and complex diseases. GWAS …