Molecular mechanisms in autoimmune thyroid disease

H Vargas-Uricoechea - Cells, 2023 - mdpi.com
The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …

Heat of the night: sleep disturbance activates inflammatory mechanisms and induces pain in rheumatoid arthritis

MR Irwin, RH Straub, MT Smith - Nature Reviews Rheumatology, 2023 - nature.com
Sleep has a homeostatic role in the regulation of the immune system and serves to constrain
activation of inflammatory signalling and expression of cellular inflammation. In patients with …

Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019

D Wu, Y Jin, Y Xing, MD Abate, M Abbasian… - …, 2023 - thelancet.com
Background The causes for immune-mediated inflammatory diseases (IMIDs) are diverse
and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to …

Regulatory mechanism of M1/M2 macrophage polarization in the development of autoimmune diseases

Y Peng, M Zhou, H Yang, R Qu, Y Qiu… - Mediators of …, 2023 - Wiley Online Library
Macrophages are innate immune cells in the organism and can be found in almost tissues
and organs. They are highly plastic and heterogeneous cells and can participate in the …

Advanced methods and novel biomarkers in autoimmune diseases‑a review of the recent years progress in systemic lupus erythematosus

KA Fenton, HL Pedersen - Frontiers in Medicine, 2023 - frontiersin.org
There are several autoimmune and rheumatic diseases affecting different organs of the
human body. Multiple sclerosis (MS) mainly affects brain, rheumatoid arthritis (RA) mainly …

Roles of interferon induced protein with tetratricopeptide repeats (IFIT) family in autoimmune disease

YY Wu, J Xing, XF Li, YL Yang, H Shao, J Li - Autoimmunity Reviews, 2023 - Elsevier
Interferon-induced tetrapeptide repeat (IFIT) family proteins are an important component of
the antiviral immune response. There are four known members of the human IFIT family …

Beyond very early systemic sclerosis: deciphering pre‑scleroderma and its trajectories to open new avenues for preventive medicine

A Lescoat, S Bellando-Randone… - The Lancet …, 2023 - thelancet.com
The identification of individuals with systemic sclerosis in an oligosymptomatic phase
preceding the very early manifestations of the disease represents a challenge in the search …

Daratumumab for autoimmune diseases: a systematic review

MT Holzer, N Ruffer, TB Huber, I Kötter, L Ostendorf… - RMD open, 2023 - rmdopen.bmj.com
Objective Refractory autoimmune diseases remain a significant challenge in clinical practice
and new therapeutic options are needed. This systematic review evaluates the existing …

Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases

L Zeng, K Yang, G Yu, W Hao, X Zhu, A Ge… - Cell Death & …, 2024 - nature.com
Autoimmune diseases commonly affect various systems, but their etiology and pathogenesis
remain unclear. Currently, increasing research has highlighted the role of ferroptosis in …

Artemisinins: Promising drug candidates for the treatment of autoimmune diseases

X Gao, X Lin, Q Wang, J Chen - Medicinal Research Reviews, 2024 - Wiley Online Library
Autoimmune diseases are characterized by the immune system's attack on one's own
tissues which are highly diverse and diseases differ in severity, causing damage in virtually …