Numerous diseases such as cancer, diabetes, cardiovascular, neurodegenerative diseases,
etc. are linked with overproduction of reactive oxygen species (ROS) and oxidative stress …

Skeletal muscle atrophy is the decrease in muscle mass and strength caused by reduced
protein synthesis/accelerated protein degradation. Various conditions, such as denervation …

Nutritional status provides metabolic substrates to activate AMP-Activated Protein Kinase
(AMPK), the energy sensor that regulates metabolism. Recent evidence has demonstrated …

ABSTRACT Apigenin (4,'5, 7-trihydroxyflavone) is one of the most studied flavonoids with
low toxicity and abundantly present phenolic compound in the plant kingdom. The main …

Apigenin is a flavonoid with antioxidant, anti-inflammatory, and anti-apoptotic activity. In this
study, the potential effects of apigenin on cardiometabolic diseases were investigated in vivo …

Obesity is associated with biological dysfunction in skeletal muscle. As a condition of obesity
accompanied by muscle mass loss and physical dysfunction, sarcopenic obesity (SO) has …

The skeletal muscle (SkM) is the largest organ, which plays a vital role in controlling
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …

Imbalance of protein homeostasis, with excessive protein degradation compared with
protein synthesis, leads to the development of muscle atrophy resulting in a decrease in …

Skeletal muscle atrophy in the aged causes loss in muscle mass and functions. Naturally
occurring antioxidant flavonoid apigenin is able to ameliorate obesity-and denervation …

Background Obesity leads to a decline in the exercise capacity of skeletal muscle, thereby
reducing mobility and promoting obesity-associated health risks. Dietary intervention has …