Neurobiology of cancer: the role of β-adrenergic receptor signaling in various tumor environments

B Mravec, L Horvathova, L Hunakova - International journal of molecular …, 2020 - mdpi.com
The development and progression of cancer depends on both tumor micro-and
macroenvironments. In addition, psychosocial and spiritual “environments” might also affect …

Contribution of adrenergic mechanisms for the stress‐induced breast cancer carcinogenesis

D Silva, C Quintas, J Gonçalves… - Journal of Cellular …, 2022 - Wiley Online Library
Breast cancer is the most common and deadliest type of cancer in women. Stress exposure
has been associated with carcinogenesis and the stress released neurotransmitters …

The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cells

J Liang, M Seghiri, PK Singh, HG Seo… - Proceedings of the …, 2024 - National Acad Sciences
While the existence and functional role of class C G-protein-coupled receptors (GPCR)
dimers is well established, there is still a lack of consensus regarding class A and B GPCR …

[HTML][HTML] Exploring neurotransmitters and their receptors for breast cancer prevention and treatment

RQ Li, XH Zhao, Q Zhu, T Liu, H Hondermarck… - Theranostics, 2023 - ncbi.nlm.nih.gov
While psychological factors have long been linked to breast cancer pathogenesis and
outcomes, accumulating evidence is revealing how the nervous system contributes to breast …

Role of semaphorins, neuropilins and plexins in cancer progression

P Fernández-Nogueira, P Linzoain-Agos… - Cancer Letters, 2024 - Elsevier
Progress in understanding nervous system-cancer interconnections has emphasized the
functional role of semaphorins (SEMAs) and their receptors, neuropilins (NRPs) and plexins …

Cancer and stress: does it make a difference to the patient when these two challenges collide?

A Iftikhar, M Islam, S Shepherd, S Jones, I Ellis - Cancers, 2021 - mdpi.com
Simple Summary Head and neck cancers are the sixth most common cancer in the world.
The burden of the disease has remained challenging over recent years despite the …

Cancer catecholamine conundrum

H Wackerhage, JF Christensen, M Ilmer… - Trends in cancer, 2022 - cell.com
Exercise, psychosocial stress, and drugs such as adrenergic agonists and antagonists
increase the concentrations of catecholamines and/or alter adrenergic signaling …

Different methylation signatures at diagnosis in patients with high-risk myelodysplastic syndromes and secondary acute myeloid leukemia predict azacitidine response …

M Cabezón, R Malinverni, J Bargay, B Xicoy… - Clinical …, 2021 - Springer
Background Epigenetic therapy, using hypomethylating agents (HMA), is known to be
effective in the treatment of high-risk myelodysplastic syndromes (MDS) and acute myeloid …

Spatially resolved transcriptomics revealed local invasion-related genes in colorectal cancer

HT Liu, SY Chen, LL Peng, L Zhong, L Zhou… - Frontiers in …, 2023 - frontiersin.org
Objective Local invasion is the first step of metastasis, the main cause of colorectal cancer
(CRC)-related death. Recent studies have revealed extensive intertumoral and intratumoral …

Stress in metastatic breast cancer: to the bone and beyond

C Lourenço, F Conceição, C Jerónimo, M Lamghari… - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is the most common cancer affecting women of all ages
worldwide. In spite of the encouraging advances made in early diagnosis, 10% of breast …