A comprehensive review on the role of the gut microbiome in human neurological disorders

SG Sorboni, HS Moghaddam… - Clinical microbiology …, 2022 - Am Soc Microbiol
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The global prevalence of autism spectrum disorder: a comprehensive systematic review and meta-analysis

N Salari, S Rasoulpoor, S Rasoulpoor… - Italian Journal of …, 2022 - Springer
Background Autism spectrum disorder (ASD) is one of the serious developmental disorders
that is usually diagnosed below the age of three years. Although the severity of the disease's …

Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS

TE Faust, G Gunner, DP Schafer - Nature Reviews Neuroscience, 2021 - nature.com
Almost 60 years have passed since the initial discovery by Hubel and Wiesel that changes
in neuronal activity can elicit developmental rewiring of the central nervous system (CNS) …

Sex and gender in neurodevelopmental conditions

S Bölte, J Neufeld, PB Marschik, ZJ Williams… - Nature Reviews …, 2023 - nature.com
Health-related conditions often differ qualitatively or quantitatively between individuals of
different birth-assigned sexes and gender identities, and/or with different gendered …

Genetic causes and modifiers of autism spectrum disorder

L Rylaarsdam, A Guemez-Gamboa - Frontiers in cellular …, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …

An overview of the main genetic, epigenetic and environmental factors involved in autism spectrum disorder focusing on synaptic activity

E Masini, E Loi, AF Vega-Benedetti, M Carta… - International journal of …, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects social
interaction and communication, with restricted interests, activity and behaviors. ASD is highly …

Composition of gut microbiota in children with autism spectrum disorder: a systematic review and meta-analysis

L Iglesias-Vázquez, G Van Ginkel Riba, V Arija… - Nutrients, 2020 - mdpi.com
Background: Autism spectrum disorder (ASD) is a public health problem and has a
prevalence of 0.6%–1.7% in children. As well as psychiatric symptoms, dysbiosis and …

Early-life differences in the gut microbiota composition and functionality of infants at elevated likelihood of developing autism spectrum disorder

S Zuffa, P Schimmel, A Gonzalez-Santana… - Translational …, 2023 - nature.com
Evidence from cross-sectional human studies, and preliminary microbial-based intervention
studies, have implicated the microbiota-gut-brain axis in the neurobiology of autism …

Oxidative stress in autism spectrum disorder—current progress of mechanisms and biomarkers

X Liu, J Lin, H Zhang, NU Khan, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a type of neurodevelopmental disorder that has been
diagnosed in an increasing number of children around the world. Existing data suggest that …

Autism spectrum disorders: etiology and pathology

AK Sauer, J Stanton, S Hans… - Exon Publications, 2021 - exonpublications.com
Autism spectrum disorders (ASD) are a group of neurodevelopmental diseases. The cause
of ASD is unknown, but several genetic and non-genetic risk factors have been …