The urgent need for new therapies for some devastating neuromuscular diseases (NMDs),
such as Duchenne muscular dystrophy or amyotrophic lateral sclerosis, has led to an …

The X‐linked inherited neuromuscular disorder Duchenne muscular dystrophy is
characterised by primary abnormalities in the membrane cytoskeletal component dystrophin …

Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by absence of the
protein dystrophin, which acts as a structural link between the basal lamina and contractile …

Per-and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants
known to pose significant risks to human and wildlife health. Freshwater turtles (Emydura …

Muscle diseases cover a diverse group of disorders that, in most cases, are hereditary. The
rarity of the individual muscle diseases provides a challenge for researchers when wanting …

Background Multiple clinical trials to assess the efficacy of AAV-directed gene transfer in
participants with Duchenne muscular dystrophy (DMD) are ongoing. The success of these …

Limb girdle muscular dystrophies (LGMDs) are a group of genetically inherited
neuromuscular diseases with a very variable clinical presentation and overlapping traits …

Background: Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease
caused by mutations in the dystrophin gene. Due to their phenotypic similarity to human …

The absence of dystrophin hypersensitizes skeletal muscle of lower and higher vertebrates
to eccentric contraction (ECC)-induced strength loss. Loss of strength can be accompanied …

Abstract Skeletal muscles account for~ 30-40% of the total weight of human body and are
responsible for its most important functions, including movement, respiration …