Immunosenescence and COVID-19

JM Witkowski, T Fulop, E Bryl - Mechanisms of ageing and development, 2022 - Elsevier
Ageing is associated with modified function of both innate and adaptive immunity. It is
believed that changes occurring in ageing immune system are responsible for increased …

Understanding COVID-19 in children: immune determinants and post-infection conditions

GA Rotulo, P Palma - Pediatric research, 2023 - nature.com
Coronavirus disease 2019 in children presents with milder clinical manifestations than in
adults. On the other hand, the presence of a wide range of inflammatory manifestations …

[HTML][HTML] Formation of eicosanoids and other oxylipins in human macrophages

O Radmark - Biochemical pharmacology, 2022 - Elsevier
In this review it is attempted to summarize current studies about formation of eicosanoids
and other oxylipins in different human macrophages. There are several reports on M1 and …

Recent progress of microneedles in transdermal immunotherapy: a review

X Ai, J Yang, Z Liu, T Guo, N Feng - International Journal of Pharmaceutics, 2024 - Elsevier
Since human skin is an immune organ, a large number of immune cells are distributed in the
epidermis and the dermis of the skin. Transdermal immunotherapy shows great therapeutic …

Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease

CA Labarrere, GS Kassab - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …

The dual role of the innate immune system in the effectiveness of mRNA therapeutics

A Muslimov, V Tereshchenko, D Shevyrev… - International journal of …, 2023 - mdpi.com
Advances in molecular biology have revolutionized the use of messenger RNA (mRNA) as a
therapeutic. The concept of nucleic acid therapy with mRNA originated in 1990 when Wolff …

Alterations in the gut microbiome and its metabolites are associated with the immune response to mucosal immunization with Lactiplantibacillus plantarum-displaying …

IC Hwang, R Vasquez, JH Song… - Frontiers in Cellular …, 2023 - frontiersin.org
Lactic acid bacteria (LAB) expressing foreign antigens have great potential as mucosal
vaccines. Our previous study reported that recombinant Lactiplantibacillus plantarum SK156 …

Monocyte distribution width (MDW) in sepsis

L Agnello, AM Ciaccio, M Vidali, A Cortegiani… - Clinica Chimica …, 2023 - Elsevier
Sepsis is a life-threatening syndrome due to a dysregulated host response to infection,
which can be caused by bacterial, viral, or fungal infection. Thus, it is crucial to know how the …

Alteration in Redox Status and Lipoprotein Profile in COVID‐19 Patients with Mild, Moderate, and Severe Pneumonia

M Lalosevic, J Kotur-Stevuljevic, J Vekic… - Oxidative medicine …, 2022 - Wiley Online Library
Background. Metabolic alterations, particularly disorders of lipoprotein metabolism in COVID‐
19, may affect the course and outcome of the disease. This study aims at evaluating the …

New insights into human immune memory from SARS‐CoV‐2 infection and vaccination

GE Hartley, ESJ Edwards, RE O'Hehir, MC van Zelm - Allergy, 2022 - Wiley Online Library
Since early 2020, the world has been embroiled in an ongoing viral pandemic with SARS‐
CoV‐2 and emerging variants resulting in mass morbidity and an estimated 6 million deaths …