In this review, we summarize the origin and advancements of iridium-catalyzed asymmetric
allylic substitution reactions during the past two decades. Since the first report in 1997, Ir …

Conspectus Metal catalyzed allylic substitution is a cornerstone of organometallic and
synthetic chemistry. Enantioselective versions have been developed with catalysts derived …

We describe a fully stereodivergent synthesis of a range of α, α-disubstituted α-amino acids
via an Ir/Cu-catalyzed α-allylation of readily available imine esters. The introduction of a Cu …

This review highlights a number of additives that can be used to make asymmetric reactions
perfect. Without changing other reaction conditions, simply adding additives can lead to …

The preparation of all possible stereoisomers of a given chiral molecule bearing multiple
stereocenters by a simple and unified method is a significant challenge in asymmetric …

We report stereodivergent allylic substitution reactions of allylic esters with prochiral
enolates derived from azaaryl acetamides and acetates to form products from addition of the …

Chiral monophosphorus ligands are playing an important role for the recent advances in
asymmetric catalysis. This review summarizes the latest progress in various asymmetric …

Distinct regio-and enantioselectivity control in copper-catalyzed vinylogous and
bisvinylogous propargylic substitution has been accomplished by using a novel chiral N, N …

An iridium‐catalyzed intramolecular asymmetric allylic dearomatization reaction of naphthol
derivatives is described. Challenges confronted in this reaction include chemoselectivity …

Asymmetric synthesis of indole-annulated medium-sized-ring compounds is developed
through an iridium-catalyzed allylic dearomatization/retro-Mannich/hydrolysis cascade …