Abstract Described by Guido Fanconi almost 100 years ago, Fanconi anemia (FA) is a rare
genetic disease characterized by developmental abnormalities, bone marrow failure (BMF) …

Transcriptional noise is proposed to participate in cell fate changes, but contributions to
mammalian cell differentiation systems, including cancer, remain associative. Cancer …

The chromatin-associated protein WDR5 is a promising target for pharmacological inhibition
in cancer. Drug discovery efforts center on the blockade of the" WIN site" of WDR5, a well …

Myelodysplastic syndromes (MDS) are clonal neoplasms of the hematopoietic stem cell that
result in aberrant differentiation of hematopoietic lineages caused by a wide range of …

Although fungi are pervasive in many environments, there are few causing diseases in
humans. Its physical and biological characteristics combine to provide an organism that can …

Despite recent advances in cancer therapy, most hematological malignancies remain
incurable. Mantle cell lymphoma (MCL), a B-cell non-Hodkin's lymphoma, and the …