Glucose transporters (GLUTs) at the blood-brain barrier maintain the continuous high glucose and energy demands of the brain. They also act as therapeutic targets and provide …
D Deng, C Xu, P Sun, J Wu, C Yan, M Hu, N Yan - Nature, 2014 - nature.com
The glucose transporter GLUT1 catalyses facilitative diffusion of glucose into erythrocytes and is responsible for glucose supply to the brain and other organs. Dysfunctional mutations …
C Grisa, S Schneider - Revista de economia e sociologia rural, 2014 - SciELO Brasil
Este artigo analisa a trajetória de construção de políticas públicas para a agricultura familiar no Brasil, procurando enfatizar as" gerações" ou referenciais de políticas públicas …
The delivery of many potentially therapeutic and diagnostic compounds to specific areas of the brain is restricted by brain barriers, of which the most well known are the blood–brain …
A Albanese, F Asmus, KP Bhatia… - European Journal of …, 2011 - Wiley Online Library
Objectives: To provide a revised version of earlier guidelines published in 2006. Background: Primary dystonias are chronic and often disabling conditions with a …
L Szablewski - Journal of Alzheimer's disease, 2017 - content.iospress.com
Neurons need a continuous supply of glucose, the major source of energy for mammalian brain metabolism. The central nervous system is protected by three main physiological cell …
S Mercimek‐Mahmutoglu, J Patel, D Cordeiro… - …, 2015 - Wiley Online Library
Objective Epilepsy is a common neurologic disorder of childhood. To determine the genetic diagnostic yield in epileptic encephalopathy, we performed a retrospective cohort study in a …
The human solute carrier (SLC) transporters are important targets for drug development. Structure-based drug discovery for SLC transporters requires the description of their …
WG Leen, J Klepper, MM Verbeek, M Leferink, T Hofste… - Brain, 2010 - academic.oup.com
Glucose transporter-1 deficiency syndrome is caused by mutations in the SLC2A1 gene in the majority of patients and results in impaired glucose transport into the brain. From 2004 …