Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

Many biological processes involve large-scale changes in membrane shape. Computer
simulations of these processes are challenging since they occur across a wide range of …

Molecular dynamics simulations have emerged as a powerful tool to study biological
systems at varied length and timescales. The conventional all-atom molecular dynamics …

We present FreeDTS software for performing computational research on biomembranes at
the mesoscale. In this software, a membrane is represented by a dynamically triangulated …

Biomembranes are two-dimensional assemblies of phospholipids that are only a few
nanometres thick, but form micrometre-sized structures vital to cellular function. Explicit …

Specialized classes of proteins, working together in a tightly orchestrated manner, induce
and maintain highly curved cellular and organelles membrane morphology. Due to the …

Lipid nanoparticles (LNPs) have been widely applied in drug and gene delivery. More than
twenty years ago, DoxilTM was the first LNPs-based drug approved by the US Food and …

Protein-mediated membrane remodeling is a ubiquitous and critical process for proper
cellular function. Inverse Bin/Amphiphysin/Rvs (I-BAR) domains drive local membrane …

At the micron scale, where cell organelles display an amazing complexity in their shape and
organization, the physical properties of a biological membrane can be better-understood …